DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ddc and AAS

DIOPT Version :9

Sequence 1:	NP_724163.1	Gene:	Ddc / 35190	FlyBaseID:	FBgn0000422	Length:	510	Species:	Drosophila melanogaster
Sequence 2:	NP_849999.1	Gene:	AAS / 816553	AraportID:	AT2G20340	Length:	490	Species:	Arabidopsis thaliana

Alignment Length:	503	Identity:	213/503 - (42%)
Similarity:	304/503 - (60%)	Gaps:	36/503 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    16 DGNGKANISPDKLDPKVSIDMEAPEFKDFAKTMVDFIAEYLENIRERRVLPEVKPGYLKPLIPDA 80
            :|:||.      |.|     |::.:.:::...||||||:|.:.|.:..||.:|:||||..|:||:
plant     3 NGSGKV------LKP-----MDSEQLREYGHLMVDFIADYYKTIEDFPVLSQVQPGYLHKLLPDS 56

  Fly    81 APEKPEKWQDVMQDIERVIMPGVTHWHSPKFHAYFPTANSYPAIVADMLSGAIACIGFTWIASPA 145
            ||:.||....|:.|:...|:||||||.||.|.||:|:.:|....:.:|||..:..:||:|:.|||
plant    57 APDHPETLDQVLDDVRAKILPGVTHWQSPSFFAYYPSNSSVAGFLGEMLSAGLGIVGFSWVTSPA 121

  Fly   146 CTELEVVMMDWLGKMLELPAEFLACSGGKGGGVIQGTASESTLVALLGAKAKKLKEVKELHPEWD 210
            .||||::::||:.|:|.||.:|:  |.|.|||||||:|||:.||.|:.|:.|.|:.|.:
plant   122 ATELEMIVLDWVAKLLNLPEQFM--SKGNGGGVIQGSASEAVLVVLIAARDKVLRSVGK------ 178

  Fly   211 EHTILGKLVGYCSDQAHSSVERAGLLGGVK------LRSVQSENHRMRGAALEKAIEQDVAEGLI 269
              ..|.|||.|.|||.||::::|..:.|:.      |.:..|.|:.:|..:|::|:.:|:..|||
plant   179 --NALEKLVVYSSDQTHSALQKACQIAGIHPENCRVLTTDSSTNYALRPESLQEAVSRDLEAGLI 241

  Fly   270 PFYAVVTLGTTNSCAFDYLDECGPVGNKHNLWIHVDAAYAGSAFICPEYRHLMKGIESADSFNFN 334
            ||:....:|||:|.|.|.|...|.:.|.:.:|.||||||||||.||||||..:.|:|:|||||.|
plant   242 PFFLCANVGTTSSTAVDPLAALGKIANSNGIWFHVDAAYAGSACICPEYRQYIDGVETADSFNMN 306

  Fly   335 PHKWMLVNFDCSAMWLKDPSWVVNAFNVDPLYLKH--DMQGSAPDYRHWQIPLGRRFRALKLWFV 397
            .|||.|.|||||.:|:||...:..|.:.:|.:||:  .......||:.||||||||||:||||.|
plant   307 AHKWFLTNFDCSLLWVKDQDSLTLALSTNPEFLKNKASQANLVVDYKDWQIPLGRRFRSLKLWMV 371

  Fly   398 LRLYGVENLQAHIRRHCNFAKQFGDLCVADSRFELAAEINMGLVCFRL-------KGSNERNEAL 455
            |||||.|.|:::||.|...||:|..|...|..||:.......||||||       |..|.||..|
plant   372 LRLYGSETLKSYIRNHIKLAKEFEQLVSQDPNFEIVTPRIFALVCFRLVPVKDEEKKCNNRNREL 436

  Fly   456 LKRINGRGHIHLVPAKIKDVYFLRMAICSRFTQSEDMEYSWKEVSAAA 503
            |..:|..|.:.:....:.....||.||.:..|:.:.::.:||.:...|
plant   437 LDAVNSSGKLFMSHTALSGKIVLRCAIGAPLTEEKHVKEAWKIIQEEA 484

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ddc	NP_724163.1	Pyridoxal_deC	70..446	CDD:278699	180/390 (46%)
AAS	NP_849999.1	PLN02880	3..490	CDD:215475	213/503 (42%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	368	1.000	Domainoid score	I180
eggNOG	1	0.900	-	-		E1_COG0076
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H618
Inparanoid	1	1.050	417	1.000	Inparanoid score	I444
OMA	1	1.010	-	-		QHG57772
OrthoDB	1	1.010	-	-		D856958at2759
OrthoFinder	1	1.000	-	-		FOG0000865
OrthoInspector	1	1.000	-	-		mtm1068
orthoMCL	1	0.900	-	-		OOG6_100572
Panther	1	1.100	-	-	LDO	PTHR11999
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X696
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	14	13.840