DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ddc and csad

DIOPT Version :9

Sequence 1:	NP_724163.1	Gene:	Ddc / 35190	FlyBaseID:	FBgn0000422	Length:	510	Species:	Drosophila melanogaster
Sequence 2:	XP_009295318.1	Gene:	csad / 492476	ZFINID:	ZDB-GENE-041114-36	Length:	544	Species:	Danio rerio

Alignment Length:	502	Identity:	121/502 - (24%)
Similarity:	210/502 - (41%)	Gaps:	52/502 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    35 DMEAPEFKDFAKTMVDFIAEYLEN----IRERRVLPEVKPGYLKPLIPDAAPEKPEKWQDVMQDI 95
            ||:..:.|.|.....:.|.|.:.|    ::| :|.....|..|:.|:.....:..|..:.::|.:
Zfish    62 DMDESDGKLFLTEAFNIIMEEILNKGRDLKE-KVCEWKDPDQLRSLLDLELRDHGECHEKLLQRV 125

  Fly    96 ERVIMPGVTHWHSPKFHAYFPTANSYPAIVADMLSGAIACIGFTWIASPACTELEVVMMDWLGKM 160
            ..|....|...| |:|.........|.|:...:::..:....:|:..:|....:|..::..|..:
Zfish   126 RDVAKYSVKTCH-PRFFNQLFAGVDYHALTGRLITETLNTSQYTYEVAPVFVLMEEEVISKLRSL 189

  Fly   161 LELPAEFLACSGGKGGGVIQGTASESTLVALLGAKAKKLKEVKELHPEWDEHTILGKLVGYCSDQ 225
            :         ...:|.|:.....|.|.:.|:..|:.....:|| ....|    ...::..:.|.|
Zfish   190 V---------GWSEGDGIFCPGGSMSNMYAINVARYWAFPQVK-TKGLW----AAPRMAIFTSQQ 240

  Fly   226 AHSSVERAGLLGGVKLRSV----QSENHRMRGAALEKAIEQDVAEGLIPFYAVVTLGTTNSCAFD 286
            :|.||::.....|:...:|    ..|:..|....||..|.|..::..:||:...|.|||...|||
Zfish   241 SHYSVKKGAAFLGIGTENVFIVQVDESGSMIPEDLEAKIVQAKSQDAVPFFVNATAGTTVQGAFD 305

  Fly   287 YLDECGPVGNKHNLWIHVDAAYAGSAFICPEYRHLMKGIESADSFNFNPHKWMLVNFDCSAMWLK 351
            .|.....:..::.:|:|||||:.||.....::|||:.|||.|:|..:||||.:|....||.:..:
Zfish   306 PLKRIADICERNGMWMHVDAAWGGSVLFSKKHRHLVAGIERANSVTWNPHKMLLTGLQCSVILFR 370

  Fly   352 D-PSWVVNAFNVDPLYL--KHDMQGSAPDYRHWQIPLGRRFRALKLWFVLRLYGVENLQAHIRRH 413
            | .:.:::..:....||  :.....::.|.....|..||:...||||.:.:..|...|...:.:.
Zfish   371 DTTNLLMHCHSAKATYLFQQDKFYDTSLDTGDKSIQCGRKVDCLKLWLMWKAIGASGLSQRVDKA 435

  Fly   414 CNFAKQFGDLCVADSRFELAAEINMGLVCF-----RLKG---SNERNEALLK-------RINGRG 463
            ....:...:.......|:|..:.....|||     .|||   |.:..|.|.|       |:..||
Zfish   436 FALTRYLVEEMEKRENFQLVCKGPFVNVCFWFIPPSLKGKENSPDYQERLSKVAPVIKERMMKRG 500

  Fly   464 HIHLVPAKIKD--VYFLRMAICSRFTQSEDMEYSWKEVSAAADEMEQ 508
            .: :|..:..|  |.|.||.:.|....::||::       ..||||:
Zfish   501 TM-MVGYQPMDEHVNFFRMVVVSPQLTTKDMDF-------FLDEMEK 539

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ddc	NP_724163.1	Pyridoxal_deC	70..446	CDD:278699	89/387 (23%)
csad	XP_009295318.1	DOPA_deC_like	140..540	CDD:99743	103/422 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0076
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810