DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ddc and CG5618

DIOPT Version :9

Sequence 1:	NP_724163.1	Gene:	Ddc / 35190	FlyBaseID:	FBgn0000422	Length:	510	Species:	Drosophila melanogaster
Sequence 2:	NP_649211.1	Gene:	CG5618 / 40241	FlyBaseID:	FBgn0036975	Length:	510	Species:	Drosophila melanogaster

Alignment Length:	495	Identity:	124/495 - (25%)
Similarity:	207/495 - (41%)	Gaps:	82/495 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    61 ERRVLPEVKPGYLKPLIPDAAPEKPE-KWQDVMQDIERVIMPGVTHWHSPKFH-AYFPTANSY-- 121
            :::::|.::|..||.||.....|... ...::.:..::||...|...|. :|| ..|...:.:
  Fly    47 KQKIVPFLQPDKLKELINLKVRETENCSLAEIEELCQQVIHYSVKTSHG-RFHNQLFGQLDPFGL 110

  Fly   122 -PAIVADMLSGAIACIGFTWIASPACTELEVVMMDWLGKMLELPAEFLACSGGK-GGGVIQGTAS 184
             .|:|.:.::|:.    :|:..:|..:.:|.          |:.|.....:|.| |.|:.....|
  Fly   111 AGALVTEAMNGST----YTYEVAPVFSLIET----------EVIATICKLAGYKEGDGIFAPGGS 161

  Fly   185 ESTLVALLGAKAKKLKEVKE-----LHPEWDEHTILGKLVGYCSDQAHSSVERAGL---LGGVKL 241
            .|.:..::.|:.|...|||.     :.|          ||.:.||::|.|..:|..   ||....
  Fly   162 TSNMYGMVLARYKIAPEVKTSGMFGMRP----------LVLFTSDESHYSFVKAANWLGLGSYNC 216

  Fly   242 RSVQSENHRMRGAALEKAIEQDVAE----GLIPFYAVVTLGTTNSCAFDYLDECGPVGNKHNLWI 302
            .||::..   ||..|...:|..:||    |..||:...|.|||...|||.::....|..:|.||:
  Fly   217 VSVRTNE---RGQMLLDDLEAKIAEAKARGGEPFFVNCTAGTTVLGAFDDINGAADVTERHGLWL 278

  Fly   303 HVDAAYAGSAFICPEYRHLMKGIESADSFNFNPHKWMLVNFDCSAMWLKDPSWVV---NAFNVDP 364
            ||||...|:|.:..:.|.|:.|:|.|:||::||||.:.....||....::...::   |:.....
  Fly   279 HVDACLGGAALLSAKNRSLIAGLERANSFSWNPHKTIGAPLQCSLFLTRESGRLLERCNSTEAHY 343

  Fly   365 LYLKHDMQGSAPDYRHWQIPLGRRFRALKLWFVL--RLYGVENLQA----HIRRHCNFAKQFGDL 423
            |:.:......:.|..:..:..||:..|.|.|.:|  |.||...|..    ||.|...     |.|
  Fly   344 LFQQDKFYDVSYDTGNKSVQCGRKIDAFKFWLMLKARGYGKYGLMVDHAIHIARLLE-----GKL 403

  Fly   424 CVADSRFELA-AEINMGLVCF-------RLKGSNERNE------ALLKRI------NGRGHIHLV 468
            .....||.|. .|.....|||       |:....|..|      .:..:|      :|...|...
  Fly   404 RQRGDRFRLVIPEHEYSNVCFWFIPKAMRVSSEEETPEWWSRLYTVAPKIKEQMAHSGTLMIGYS 468

  Fly   469 PAKIKDV-YFLRMAI-CSRFTQSEDMEYSWKEVSAAADEM 506
            |.|.|:: .|.||.. |....:|:::::...|:....:::
  Fly   469 PLKAKNLGNFFRMVFTCFPILKSKELDFILDEIERLGEKI 508

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ddc	NP_724163.1	Pyridoxal_deC	70..446	CDD:278699	109/410 (27%)
CG5618	NP_649211.1	AAT_I	97..504	CDD:302748	113/438 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0076
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.810