Protein Alignment Ddc and GADL1

DIOPT Version :9

• Sequence 1: NP_724163.1
• Gene: Ddc / 35190
• FlyBaseID: FBgn0000422
• Length: 510
• Species: Drosophila melanogaster
• Sequence 2: NP_997242.2
• Gene: GADL1 / 339896
• HGNCID: 27949
• Length: 521
• Species: Homo sapiens
• Alignment Length: 510
• Identity: 134/510 - (26%)
• Similarity: 210/510 - (41%)
• Gaps: 78/510 - (15%)

  Fly    45 AKTMVDFIAEYLENIRERRVLPEV----------KPGYLKPLIP----DAAPEKPEKWQDVMQDI 95
            ||....|:.|....|.|..||...          .|..||.|:.    |:. |.|.|..::.:|
Human    42 AKAGEKFVEEACRLIMEEVVLKATDVNEKVCEWRPPEQLKQLLDLEMRDSG-EPPHKLLELCRD- 104

  Fly    96 ERVIMPGVTHW----HSPKFHAYFPTANSYPAIVADMLSGAIACIGFTWIASPACTELEVVMMDW 156
                   |.|:    :.|:|.........|.::||..::.|:....:|:..||....:|..:
Human   105 -------VIHYSVKTNHPRFFNQLYAGLDYYSLVARFMTEALNPSVYTYEVSPVFLLVEEAV--- 159

  Fly   157 LGKMLELPAEFLACSGGKGGGVIQGTASESTLVALLGAKAKKLKEVKELHPEWDEHTILGKLVGY 221
            |.||:    ||:...  :|.|:.....|.|.:.|:..|:.|...::||.........||     :
Human   160 LKKMI----EFIGWK--EGDGIFNPGGSVSNMYAMNLARYKYCPDIKEKGLSGSPRLIL-----F 213

  Fly   222 CSDQAHSSVERAGLLGGVKLRS---VQSENH-RMRGAALEKAIEQDVAEGLIPFYAVVTLGTTNS 282
            .|.:.|.|:::|....|:...:   |:::.. :|....|||.:.|...||..||....|.|||..
Human   214 TSAECHYSMKKAASFLGIGTENVCFVETDGRGKMIPEELEKQVWQARKEGAAPFLVCATSGTTVL 278

  Fly   283 CAFDYLDECGPVGNKHNLWIHVDAAYAGSAFICPEYRHLMKGIESADSFNFNPHKWMLVNFDCSA 347
            .|||.|||...:..:|:||:||||::.|||.:..::|.|:.||..|||..:||||.::....|.|
Human   279 GAFDPLDEIADICERHSLWLHVDASWGGSALMSRKHRKLLHGIHRADSVAWNPHKMLMAGIQCCA 343

  Fly   348 MWLKDPSWVVN---------AFNVDPLYLKHDMQGSAPDYRHWQIPLGRRFRALKLWFVLRLYGV 403
            :.:||.|.::.         .|..|..|   |:.....|.   .|...||..|.|.|...:..|.
Human   344 LLVKDKSDLLKKCYSAKASYLFQQDKFY---DVSYDTGDK---SIQCSRRPDAFKFWMTWKALGT 402

  Fly   404 ENLQAHIRRHCNFAKQFGDLCVADSRFELAAEINMGLVCF-----RLKGSNERNE---------- 453
            ..|:..:.|....::...|.......|:|..|.....:||     .|:...|..|
Human   403 LGLEERVNRALALSRYLVDEIKKREGFKLLMEPEYANICFWYIPPSLREMEEGPEFWAKLNLVAP 467

  Fly   454 ALLKRINGRGHIHL--VPAKIKDVYFLRMAICSRFTQSEDMEYSWKEVSAAADEM 506
            |:.:|:..:|.:.|  .|.:.| |.|.|..:.|.....|||::...|:.....:|
Human   468 AIKERMMKKGSLMLGYQPHRGK-VNFFRQVVISPQVSREDMDFLLDEIDLLGKDM 521

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ddc	NP_724163.1	Pyridoxal_deC	70..446	CDD:278699	108/401 (27%)
GADL1	NP_997242.2	AAT_I	77..445	CDD:302748	108/396 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0076
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810