DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ddc and CG1486

DIOPT Version :9

Sequence 1:	NP_724163.1	Gene:	Ddc / 35190	FlyBaseID:	FBgn0000422	Length:	510	Species:	Drosophila melanogaster
Sequence 2:	NP_608450.1	Gene:	CG1486 / 33108	FlyBaseID:	FBgn0031174	Length:	852	Species:	Drosophila melanogaster

Alignment Length:	500	Identity:	97/500 - (19%)
Similarity:	163/500 - (32%)	Gaps:	159/500 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MSHIPISNT----IPTKQTDGNGKANISPDKLDPKVSIDMEAPEFKDFAKTMVDFIA-------- 53
            :.::.:|.|    .|.:..:..|:...|.|.|..|..:.      .|..|::...::
  Fly    56 LENVKVSTTPESPNPVENEEEAGERVTSEDLLPAKHRVP------SDILKSLEQLVSYTDSDDDP 114

  Fly    54 EY----LENIRERRVLPEVKPGYLKPLIPDAAPEKPEKWQDVMQDIERV---IMPGVTHWHSPKF 111
            |:    |:::....::......||..|              ..|.:.||   |....|.|....|
  Fly   115 EFPLPALDDVSHLALISHSIVAYLSHL--------------DRQQLLRVTNSISGDATRWLGTLF 165

  Fly   112 HAYFPTANSYPAIVADMLSGAIACIGFTWIASPACTELEVVMMDWLGKMLELPAEFLACSGGKGG 176
            |...| |:|:.|..||.:                   |..|.:          |....|.|...|
  Fly   166 HFAHP-ASSFHADNADAV-------------------LRTVRL----------AIVARCPGYLEG 200

  Fly   177 GVIQGTASESTLVALLGAKAKKLKEVKELHPEWDEHTILGKLVGYCSD-----QAHSSVERAGL- 235
            |:                            |...:.|.      |.|:     :.|.:..:.|:
  Fly   201 GI----------------------------PALAQPTF------YISENTTPMRLHYACRQLGIP 231

  Fly   236 LGGVKLRSVQSENHRMRGAALEKAIEQDVAEGLIPFYAVVTLGTTNSCAFDYLDECGPVGNKHNL 300
            |..:|:....|::..|....|:|.|:|||.....|...|..:|.:.....|.|.....|...||:
  Fly   232 LEAIKVIPEHSQSGTMDVTLLQKQIQQDVGNNRTPLLVVADIGASLCGYVDNLLRLRDVCKAHNM 296

  Fly   301 WIHVDAAYAGSAFICPEYR-HLMKGIESADSFNFNPHKWMLVNFDCSAMWLKDPSWVVNAFNVDP 364
            |:|. :.:..:|.:|.:.: |:.:.:.|           |.:|.   ..||..||.        |
  Fly   297 WLHA-SGHGLAALVCAQNQGHVEEVLHS-----------MALNL---GSWLGVPSL--------P 338

  Fly   365 LYLKH-DMQGSAPDYRHWQIPLGRRFRALKLWFVLRLYGVENL--QAHIR-RHCNFAKQFGDLC- 424
            :.|.| .:|.||.........|.||..||.||..|:..|.:.:  :.|:. :.|:...:....|
  Fly   339 IVLLHRPLQNSALSAFESDPILSRRLNALSLWTSLQALGRKAIAERLHVAFQTCSILFEIASKCE 403

  Fly   425 -------------------VADSRFELAAEINMG--LVCFRLKGS 448
                               |..|.|::.|..:..  :|.::..||
  Fly   404 GIRVLSHTPGAQTGASLSDVIQSPFDVQALFDAAAPVVAYQFDGS 448

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ddc	NP_724163.1	Pyridoxal_deC	70..446	CDD:278699	83/411 (20%)
CG1486	NP_608450.1	AAT_I	159..>384	CDD:302748	67/311 (22%)
CG1486	NP_608450.1	WWbp	<725..801	CDD:304964
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45445351
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.840