Protein Alignment Ddc and gad1.2

DIOPT Version :10

• Sequence 1: NP_724163.1
• Gene: Ddc / 35190
• FlyBaseID: FBgn0000422
• Length: 510
• Species: Drosophila melanogaster
• Sequence 2: XP_012819752.1
• Gene: gad1.2 / 100145511
• XenbaseID: XB-GENE-5830282
• Length: 554
• Species: Xenopus tropicalis
• Alignment Length: 455
• Identity: 112/455 - (24%)
• Similarity: 191/455 - (41%)
• Gaps: 65/455 - (14%)

  Fly    83 EKPEKWQDVMQDIERVIMPGVTHWHSPKFHAYFPTANSYPAIVADMLSGAIACIGFT--WIASPA 145
            ::||..:.::.|....:...:...| |:   ||           :.||..:..||..  |:.:.|
 Frog   120 DQPEPLEQILVDCSDTLKYSIKTGH-PR---YF-----------NQLSCGLDIIGLAGEWLTATA 169

  Fly   146 CTEL---EV----VMMDWLGKMLELPAEFLACSGGKGGGVIQGTASESTLVALLGAKAKKLKEVK 203
            .|.:   |:    ::|:.:  :|:...|.:.....:..|:.....:.|.|.:|..|:.|....||
 Frog   170 NTNMFTYEIAPVFIIMEEI--VLKKMQEIIGWGENEADGIFSPGGTISNLYSLQAARYKYFPMVK 232

  Fly   204 ELHPEWDEHTILGKLVGYCSDQAHSSVERAGLLGGVKLRSVQS----ENHRMRGAALEKAIEQDV 264
            .     .....|.::|.:.|:|:|.|.::|..:.|:...:|.:    |..:|..:.||..|.:..
 Frog   233 T-----KGMAALPQIVIFTSEQSHYSFKKASAILGIGTDNVIAIKCDERGKMIPSDLEDKILKAK 292

  Fly   265 AEGLIPFYAVVTLGTTNSCAFDYLDECGPVGNKHNLWIHVDAAYAGSAFICPEYRHLMKGIESAD 329
            .:|..|||...|.|||...|||.|.....:..::.||:|||||:.|...:..::|:.|.|||.|:
 Frog   293 RQGQHPFYVSATAGTTVYGAFDPLITIADICKRYGLWMHVDAAWGGGLLLSKKHRYKMNGIERAN 357

  Fly   330 SFNFNPHKWMLVNFDCSAMWLKDPSWVVNAFN---VDPLYLKHDMQGSAPDYRHWQIPLGRRFRA 391
            |..:||||.|.|...|||:.::... ::.|.|   .|.|:.......:|.|.....|..||....
 Frog   358 SVTWNPHKIMGVPLQCSAILIRQKG-LLQACNQQCADYLFQMDKPYDTAYDTGDKTIQCGRHVDI 421

  Fly   392 LKLWFVLRLYGVENLQAHIRRHCNFAKQFGDLCVADSRFELAAE-----INMGLVCF-------- 443
            .|||.:.:..|....:..|.|....::...:...:.|.|||...     .|   |||
 Frog   422 FKLWLMWKAKGSCGFELQINRCLELSEYLYNKLQSKSNFELVFRDKPEYTN---VCFWYIPPSLE 483

  Fly   444 ---RLKGSNERNEALLKRINGR----GHIHL--VPAKIKDVYFLRMAICSRFTQSEDMEYSWKEV 499
               |.|....|...:..:|..|    |.:.:  .|...|..:| ||...:..::..|:::..:|:
 Frog   484 HVPRDKEWKARLHKIAPQIKARMMEEGTVMVSYQPQGDKPNFF-RMVFSNPASKKSDVDFLLEEI 547

  Fly   500  499
             Frog   548  547

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ddc	NP_724163.1	Pyridoxal_deC	70..446	CDD:395219	100/394 (25%)
gad1.2	XP_012819752.1	Pyridoxal_deC	104..478	CDD:395219	99/383 (26%)