Protein Alignment amd and SGPL1

DIOPT Version :9

• Sequence 1: NP_476592.1
• Gene: amd / 35188
• FlyBaseID: FBgn0000075
• Length: 510
• Species: Drosophila melanogaster
• Sequence 2: NP_003892.2
• Gene: SGPL1 / 8879
• HGNCID: 10817
• Length: 568
• Species: Homo sapiens
• Alignment Length: 418
• Identity: 86/418 - (20%)
• Similarity: 148/418 - (35%)
• Gaps: 112/418 - (26%)

  Fly    17 IADYLENIRDDDVLPN-----VEPGYLLDLLPTEMPEEPEAWKDVLGDISRVIKPGLTHWQSPHM 76
            |.|.| |...||:..|     |:..| :..||::            |..|..:...|..:.|  |
Human    88 IQDKL-NKTKDDISKNMSFLKVDKEY-VKALPSQ------------GLSSSAVLEKLKEYSS--M 136

  Fly    77 HAYYPTSTSYPSI------VGEMLASGFGVIGFSWI------CSPACTELEVVVMDWLAKFLKLP 129
            .|::....:..::      :.|:|...:|  .|:|.      ..|...::|       |:.:::.
Human   137 DAFWQEGRASGTVYSGEEKLTELLVKAYG--DFAWSNPLHPDIFPGLRKIE-------AEIVRIA 192

  Fly   130 AHFQHASDGPGG-GVIQGSASEAVLVAVLAAREQAVANYRESHPELSESEVRGRLVAYSSDQSNS 193
            ...  .:.||.. |.:....:|::|:|..|.|:.|.....:: ||         :||..|  :::
Human   193 CSL--FNGGPDSCGCVTSGGTESILMACKAYRDLAFEKGIKT-PE---------IVAPQS--AHA 243

  Fly   194 CIEKAGVLAAMPIRLLPAGEDFVLRGDTLRGAIEEDVAAGRIPVICVATLGTTGTCAYDDIESLS 258
            ...||.....|.|..:|..:...:....:|.||..:.|.    ::|.......|  ..|.:..::
Human   244 AFNKAASYFGMKIVRVPLTKMMEVDVRAMRRAISRNTAM----LVCSTPQFPHG--VIDPVPEVA 302

  Fly   259 AVCEEFKVWLHVDAAYAG--------GAFALEECSDLR-KGLDRVDSLNFNLHKFMLVNFDCSAM 314
            .:..::|:.|||||...|        ..:.||...|.| ||   |.|::.:.||:.......|.:
Human   303 KLAVKYKIPLHVDACLGGFLIVFMEKAGYPLEHPFDFRVKG---VTSISADTHKYGYAPKGSSLV 364

  Fly   315 WLRDANKVVDSFNVDRIYLKHKHEGQSQIPDFRHWQIPL-------GRRFRALKV--WITFRTLG 370
            ...|.......|.||                 ..||..:       |.|...:..  |......|
Human   365 LYSDKKYRNYQFFVD-----------------TDWQGGIYASPTIAGSRPGGISAACWAALMHFG 412

  Fly   371 AEGLRNHVRKHIELAKQFEQLVLKDSRF 398
            ..|       ::|..||    ::|.:||
Human   413 ENG-------YVEATKQ----IIKTARF 429

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
amd	NP_476592.1	Pyridoxal_deC	35..414	CDD:278699	78/395 (20%)
SGPL1	NP_003892.2	DOPA_deC_like	144..507	CDD:99743	69/346 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0076
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810