Protein Alignment amd and CSAD

DIOPT Version :9

• Sequence 1: NP_476592.1
• Gene: amd / 35188
• FlyBaseID: FBgn0000075
• Length: 510
• Species: Drosophila melanogaster
• Sequence 2: XP_024304779.1
• Gene: CSAD / 51380
• HGNCID: 18966
• Length: 620
• Species: Homo sapiens
• Alignment Length: 534
• Identity: 119/534 - (22%)
• Similarity: 194/534 - (36%)
• Gaps: 150/534 - (28%)

  Fly    34 EPGYLLDLLPTEMPEEPEAWKDVLGDISRVIKPGLTHWQSPHMHAYYPTSTSYP----------- 87
            ||..|..||..|:..:.|:.|.:|.....||:              |...|.:|
Human   144 EPEELKQLLDLELRSQGESQKQILERCRAVIR--------------YSVKTGHPRFFNQLFSGLD 194

  Fly    88 --SIVGEMLASGFGVIGFSWICSPACTELEVVVMDWLAKFLKLPAHFQHAS-DG---PGGGVIQG 146
              ::.|.::........:::..:|....:|..|:      .||.|....:| ||   |||.:
Human   195 PHALAGRIITESLNTSQYTYEIAPVFVLMEEEVL------RKLRALVGWSSGDGIFCPGGSI--- 250

  Fly   147 SASEAVLVAVLAAREQAVANYRESHPELSESEVR---------------------GRLVAYSSDQ 190
                :.:.||..||.|       .:|:..:..:|                     |.|:..||..
Human   251 ----SNMYAVNLARYQ-------RYPDCKQRGLRTLPPLALFTSKEVGKRHRPNPGLLILISSHV 304

  Fly   191 SNSCIEKAGVLAAMPI-----RLLPAG-----------------------EDFVLRGDTLRGAIE 227
            :.....:.......|.     ||:..|                       |.|:|
Human   305 TTPSRRELRFWDLAPTVSEWSRLMREGKWSPRIWRGRLVWPRLRLTFHFFETFIL---------- 359

  Fly   228 EDVAAGRIPVICVATLGTTGTCAYDDIESLSAVCEEFKVWLHVDAAYAGGAFALEECSDLRKGLD 292
               .:|.:|.:..||.|||...|:|.:|:::.||:...:|||||||:.|.....:....|..|:.
Human   360 ---DSGAVPFLVSATSGTTVLGAFDPLEAIADVCQRHGLWLHVDAAWGGSVLLSQTHRHLLDGIQ 421

  Fly   293 RVDSLNFNLHKFMLVNFDCSAMWLRDANKVVDSFNVDRIYLKHKHEGQSQ--IPDFRHWQIPL-- 353
            |.||:.:|.||.:.....|||:.|:|.:.:          ||..|..|:.  ....:.:.:.|
Human   422 RADSVAWNPHKLLAAGLQCSALLLQDTSNL----------LKRCHGSQASYLFQQDKFYDVALDT 476

  Fly   354 -------GRRFRALKVWITFRTLGAEGLRNHVRKHIELAKQFEQLVLKDSRFELVAPRALGLVCF 411
                   |||...||:|:.::..|.:||...:.:...||:...:.:.|...||||.......|||
Human   477 GDKVVQCGRRVDCLKLWLMWKAQGDQGLERRIDQAFVLARYLVEEMKKREGFELVMEPEFVNVCF 541

  Fly   412 -------RPKGD--------NEITTQLLQRLMDRKKIYMVKAEHAGR-QFLRFVVCGMDTKASDI 460
                   |.|.:        :::...|.:|::....:.:....|..| .|.|.||.......:|:
Human   542 WFVPPSLRGKQESPDYHERLSKVAPVLKERMVKEGSMMIGYQPHGTRGNFFRVVVANSALTCADM 606

  Fly   461 DFAWQEIESQLTDL 474
            ||...|:|....||
Human   607 DFLLNELERLGQDL 620

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
amd	NP_476592.1	Pyridoxal_deC	35..414	CDD:278699	102/462 (22%)
CSAD	XP_024304779.1	DOPA_deC_like	185..616	CDD:99743	103/473 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0076
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810