Protein Alignment amd and gad1b

DIOPT Version :10

• Sequence 1: NP_476592.1
• Gene: amd / 35188
• FlyBaseID: FBgn0000075
• Length: 510
• Species: Drosophila melanogaster
• Sequence 2: NP_919400.1
• Gene: gad1b / 378441
• ZFINID: ZDB-GENE-030909-3
• Length: 587
• Species: Danio rerio
• Alignment Length: 517
• Identity: 129/517 - (24%)
• Similarity: 215/517 - (41%)
• Gaps: 87/517 - (16%)

  Fly     8 EFGKAAIDYIADYLENI--RDDDVLPNVEPGYLLDLLP---TEMPEEPEAWKDVLGDISRVIKPG 67
            :|....::.:.:|:...  |...||....|..||:.:.   .|:.::||:.:.:|.|....:|
Zfish   108 QFLLEVVEILTNYVRKTFDRSTKVLDFHHPHQLLEGMEGFNLELSDQPESLEQILVDCRDTLK-- 170

  Fly    68 LTHWQSPHMHAYYPTSTSYPSIVGEMLASGFGVIGFS--WICSPACTEL---EV----VVMDWLA 123
                        |...|.:|....: |:||..:||.:  |:.|.|.|.:   |:    |:|:.|.
Zfish   171 ------------YGVRTGHPRFFNQ-LSSGLDIIGLAGEWLTSTANTNMFTYEIAPVFVLMEQLT 222

  Fly   124 KFLKLPAHFQHASDGPGGGVIQGSASEAVLVAVLAAREQAVANYRESHPELSESEVRG-----RL 183
              ||.........:|.|..:.....:.:.:.:|:.||          :....|.:.:|     ||
Zfish   223 --LKKMREIIGWPNGDGDALFSPGGAISNMYSVMVAR----------YKYFPEVKTKGMSAAPRL 275

  Fly   184 VAYSSDQSNSCIEKAGVLAAMPIRLLPAGEDFVL------RGDTLRGAIEEDV----AAGRIPVI 238
            |.::|:.|:..|:|||.       :|..|::.|:      ||..:...:|..|    ..|.:|:.
Zfish   276 VLFTSEHSHYSIKKAGA-------VLGFGKENVILLKTDERGRVIPADLEAKVIDAKQKGYVPLF 333

  Fly   239 CVATLGTTGTCAYDDIESLSAVCEEFKVWLHVDAAYAGGAFALEECSDLRKGLDRVDSLNFNLHK 303
            ..||.|||...|:|.|..::.:||::.:|||||.|:.||.....:......|::|.:|:.:|.||
Zfish   334 VNATAGTTVYGAFDPINDIADICEKYNLWLHVDGAWGGGLLMSRKHRHKLSGIERANSVTWNPHK 398

  Fly   304 FMLVNFDCSAMWLRDANKVVDSFNVDRIYLKHKHEGQSQIPDFRHWQIPLGRRFRALKVWITFRT 368
            .|.|...|||:.:|:...:....::...||....:......|.....|..||.....|.|:.::.
Zfish   399 MMGVPLQCSAILVREKGILQGCNSMCAGYLFQPDKQYDVTYDTGDKAIQCGRHVDIFKFWLMWKA 463

  Fly   369 LGAEGLRNHVRKHIELAKQFEQLVLKDSRFELV---APRALGLVCF---------RPKGDNEITT 421
            .|..|...|:.:.:||::.....:.....:|:|   .|:... |||         .|.||..  .
Zfish   464 KGTIGFEQHIDRCLELSEYLYNKIKNREGYEMVFEGQPQHTN-VCFWYIPPSLRGMPNGDER--R 525

  Fly   422 QLLQRLMDRKKIYMVK--AEHAGRQ-------FLRFVVCGMDTKASDIDFAWQEIESQLTDL 474
            :.|.|:..:.|..|::  ....|.|       |.|.||.......|||||...|||....||
Zfish   526 EKLHRVAPKIKAMMMECGTTMVGYQPQGDKVNFFRMVVSNHAVTKSDIDFLIDEIERLGQDL 587

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
amd	NP_476592.1	Pyridoxal_deC	35..414	CDD:395219	101/417 (24%)
gad1b	NP_919400.1	Pyridoxal_deC	137..511	CDD:395219	101/408 (25%)