Protein Alignment amd and Hdc

DIOPT Version :9

• Sequence 1: NP_476592.1
• Gene: amd / 35188
• FlyBaseID: FBgn0000075
• Length: 510
• Species: Drosophila melanogaster
• Sequence 2: NP_001260855.1
• Gene: Hdc / 36076
• FlyBaseID: FBgn0005619
• Length: 847
• Species: Drosophila melanogaster
• Alignment Length: 481
• Identity: 231/481 - (48%)
• Similarity: 323/481 - (67%)
• Gaps: 3/481 - (0%)

  Fly     1 MDAKEFREFGKAAIDYIADYLENIRDDDVLPNVEPGYLLDLLPTEMPEEPEAWKDVLGDISRVIK 65
            ||.||:|:.||..:|||||||||||:..|.|:|.|||:..|||...|.|.|.|..:..|:.|::.
  Fly     1 MDFKEYRQRGKEMVDYIADYLENIRERRVFPDVSPGYMRQLLPESAPIEGEPWPKIFSDVERIVM 65

  Fly    66 PGLTHWQSPHMHAYYPTSTSYPSIVGEMLASGFGVIGFSWICSPACTELEVVVMDWLAKFLKLPA 130
            ||:|||||||||||:|...|.||::|:|||.....:||:|..||||||||::||:||.|.:.||.
  Fly    66 PGITHWQSPHMHAYFPALNSMPSLLGDMLADAINCLGFTWASSPACTELEIIVMNWLGKMIGLPD 130

  Fly   131 HFQH-ASDGPGGGVIQGSASEAVLVAVLAAREQAVANYRESHPELSESEVRGRLVAYSSDQSNSC 194
            .|.| :|...||||:|.:||||.||.:||.|.:|:..:.|.||...::|:..|||||.|||::|.
  Fly   131 AFLHLSSQSQGGGVLQTTASEATLVCLLAGRTRAIQRFHERHPGYQDAEINARLVAYCSDQAHSS 195

  Fly   195 IEKAGVLAAMPIRLLPAGEDFVLRGDTLRGAIEEDVAAGRIPVICVATLGTTGTCAYDDIESLSA 259
            :|||.::..:.:|.:.|.:|..:||..||.|||:|:..|.:|....|||||||:|::|::|.:..
  Fly   196 VEKAALIGLVRMRYIEADDDLAMRGKLLREAIEDDIKQGLVPFWVCATLGTTGSCSFDNLEEIGI 260

  Fly   260 VCEEFKVWLHVDAAYAGGAFALEECSDLRKGLDRVDSLNFNLHKFMLVNFDCSAMWLRDANKVVD 324
            ||.|..:||||||||||.||...|.....:|::|.||:.||..|:::|:||.:|:|:||:..|..
  Fly   261 VCAEHHLWLHVDAAYAGSAFICPEFRTWLRGIERADSIAFNPSKWLMVHFDATALWVRDSTAVHR 325

  Fly   325 SFNVDRIYLKHKHEGQSQIPDFRHWQIPLGRRFRALKVWITFRTLGAEGLRNHVRKHIELAKQFE 389
            :|||:.:||:|::.|.:  .||.||||||.|||||||||...|:.|.:||:.|:|:.:.||::||
  Fly   326 TFNVEPLYLQHENSGVA--VDFMHWQIPLSRRFRALKVWFVLRSYGIKGLQRHIREGVRLAQKFE 388

  Fly   390 QLVLKDSRFELVAPRALGLVCFRPKGDNEITTQLLQRLMDRKKIYMVKAEHAGRQFLRFVVCGMD 454
            .|||.|.||||.|.|.||||.||.:||||||.:||:||..|..::.:.:...|:..:||.:....
  Fly   389 ALVLADHRFELPAKRHLGLVVFRIRGDNEITEKLLKRLNHRGNLHCIPSSLKGQYVIRFTITSTH 453

  Fly   455 TKASDIDFAWQEIESQLTDLQAEQSL 480
            |...||...|.||....:.:..|.::
  Fly   454 TTLDDIVKDWMEIRQVASTVLEEMNI 479

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
amd	NP_476592.1	Pyridoxal_deC	35..414	CDD:278699	189/379 (50%)
Hdc	NP_001260855.1	Pyridoxal_deC	35..413	CDD:278699	189/379 (50%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	368	1.000	Domainoid score	I180
eggNOG	1	0.900	-	-		E1_COG0076
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D223497at33208
OrthoFinder	1	1.000	-	-		FOG0000865
OrthoInspector	1	1.000	-	-		mtm1068
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11999
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	7	6.920