Protein Alignment amd and Tdc2

DIOPT Version :9

• Sequence 1: NP_476592.1
• Gene: amd / 35188
• FlyBaseID: FBgn0000075
• Length: 510
• Species: Drosophila melanogaster
• Sequence 2: NP_724489.1
• Gene: Tdc2 / 246620
• FlyBaseID: FBgn0050446
• Length: 637
• Species: Drosophila melanogaster
• Alignment Length: 501
• Identity: 227/501 - (45%)
• Similarity: 319/501 - (63%)
• Gaps: 20/501 - (3%)

  Fly     1 MDAKEFREFGKAAIDYIADYLENIRDDDVLPNVEPGYLLDLLPTEMPEEPEAWKDVLGDISRVIK 65
            ||:.|||:.|...::||.:|||.:.:..|.|:||||||..|||.|.|:|||.|..::.|:...|.
  Fly     1 MDSTEFRKRGMEMVEYICNYLETLNERRVTPSVEPGYLRHLLPPEAPQEPEDWDQIMRDVEDKIM 65

  Fly    66 PGLTHWQSPHMHAYYPTSTSYPSIVGEMLASGFGVIGFSWICSPACTELEVVVMDWLAKFLKLPA 130
            ||:||||.|..|||:|...|:|||:|:||..|.|.|||||..||||||||.:|:|||.|.:.||.
  Fly    66 PGVTHWQHPRFHAYFPAGNSFPSILGDMLGDGIGCIGFSWAASPACTELETIVLDWLGKAIGLPD 130

  Fly   131 HFQHASDG-PGGGVIQGSASEAVLVAVLAAREQAVANYRESHPELSESEVRGRLVAYSSDQSNSC 194
            ||....:| .||||||.||||.|||.:||||.||:...:..||.:.|..:..:|:||.|.:::||
  Fly   131 HFLALKEGSTGGGVIQTSASECVLVTMLAARAQALKRLKAQHPFVEEGHLLSKLMAYCSKEAHSC 195

  Fly   195 IEKAGVLAAMPIRLLPAGEDFVLRGDTLRGAIEEDVAAGRIPVICVATLGTTGTCAYDDIESLSA 259
            :|||.::..:.:|:|...:|..|||.|:..|:|||...|.:|.....||||||:||:|::..:..
  Fly   196 VEKAAMICFVKLRILEPDDDASLRGQTIYEAMEEDELQGLVPFFVSTTLGTTGSCAFDNLPEIGK 260

  Fly   260 VCEEFK-VWLHVDAAYAGGAFALEECSDLRKGLDRVDSLNFNLHKFMLVNFDCSAMWLRDANKVV 323
            ..:.|. |||||||||||.:|...|...|.||::..||.|.|.:|::|.|||||.:|:||..::.
  Fly   261 QLQRFPGVWLHVDAAYAGNSFICPELKPLLKGIEYADSFNTNPNKWLLTNFDCSTLWVRDRIRLT 325

  Fly   324 DSFNVDRIYLKHKHEGQSQIP-DFRHWQIPLGRRFRALKVWITFRTLGAEGLRNHVRKHIELAKQ 387
            .:..||.:||||   |.|... |:|||.:||.||||:||:|...|:.|..||::::|.||:|||:
  Fly   326 SALVVDPLYLKH---GYSDAAIDYRHWGVPLSRRFRSLKLWFVLRSYGISGLQHYIRHHIKLAKR 387

  Fly   388 FEQLVLKDSRFELVAPRALGLVCFRPKGDNEITTQLLQRLMDRKKIYMVKAEHAGRQFLRFVVCG 452
            ||:|||||.|||:.....|||||||.||.:::..:||..:.:..|::||.|....|..:||....
  Fly   388 FEELVLKDKRFEICNQVKLGLVCFRLKGSDKLNEKLLSIINESGKLHMVPASVGDRYIIRFCAVA 452

  Fly   453 MDTKASDIDFAW------------QEIESQLTDL--QAEQSLVARK 484
            .:..|.|||:||            :|...:|:::  :.:|..:|:|
  Fly   453 QNATAEDIDYAWDIIVDFANELLEKEQHDELSEIMNRKKQDTLAQK 498

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
amd	NP_476592.1	Pyridoxal_deC	35..414	CDD:278699	190/381 (50%)
Tdc2	NP_724489.1	Pyridoxal_deC	35..414	CDD:278699	190/381 (50%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	368	1.000	Domainoid score	I180
eggNOG	1	0.900	-	-		E1_COG0076
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0.815392	Normalized mean entropy	S2516
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D223497at33208
OrthoFinder	1	1.000	-	-		FOG0000865
OrthoInspector	1	1.000	-	-		mtm1068
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11999
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	8	7.870