Protein Alignment amd and Hdc

DIOPT Version :10

• Sequence 1: NP_476592.1
• Gene: amd / 35188
• FlyBaseID: FBgn0000075
• Length: 510
• Species: Drosophila melanogaster
• Sequence 2: NP_058712.2
• Gene: Hdc / 24443
• RGDID: 2790
• Length: 656
• Species: Rattus norvegicus
• Alignment Length: 498
• Identity: 222/498 - (44%)
• Similarity: 311/498 - (62%)
• Gaps: 22/498 - (4%)

  Fly     1 MDAKEFREF---GKAAIDYIADYLENIRDDDVLPNVEPGYLLDLLPTEMPEEPEAWKDVLGDISR 62
            |:..|:||:   ||..:|||..||..:|:..|.|||:||||...:|:..||||::|..:.|||.:
  Rat     2 MEPSEYREYQARGKEMVDYICQYLSTLRERQVTPNVKPGYLRAQIPSSAPEEPDSWDSIFGDIEQ 66

  Fly    63 VIKPGLTHWQSPHMHAYYPTSTSYPSIVGEMLASGFGVIGFSWICSPACTELEVVVMDWLAKFLK 127
            :|.||:.||||||||||||..||:||::|:|||.....:||:|..||||||||:.:||||||.|.
  Rat    67 IIMPGVVHWQSPHMHAYYPALTSWPSLLGDMLADAINCLGFTWASSPACTELEMNIMDWLAKMLG 131

  Fly   128 LPAHF-QHASDGPGGGVIQGSASEAVLVAVLAAREQAVANYRESHPELSESEVRGRLVAYSSDQS 191
            ||..| .|.....||||:|.:.||:.|:|:||||:..:...:...|...||.:..|||||:|||:
  Rat   132 LPDFFLHHHPSSQGGGVLQSTVSESTLIALLAARKNKILEMKAHEPNADESSLNARLVAYASDQA 196

  Fly   192 NSCIEKAGVLAAMPIRLLPAGEDFVLRGDTLRGAIEEDVAAGRIPVICVATLGTTGTCAYDDIES 256
            :|.:||||:::.:.|:.||..::|.|||:.|:.|||||...|.:||...|||||||.||:|.:..
  Rat   197 HSSVEKAGLISLVKIKFLPVDDNFSLRGEALQKAIEEDKQQGLVPVFVCATLGTTGVCAFDKLSE 261

  Fly   257 LSAVCEEFKVWLHVDAAYAGGAFALEECSDLRKGLDRVDSLNFNLHKFMLVNFDCSAMWLRDANK 321
            |..:|....:||||||||||.||...|.....||::..||..||..|:|:|:|||:..|::|..|
  Rat   262 LGPICAREGLWLHVDAAYAGTAFLCPELRGFLKGIEYADSFTFNPSKWMMVHFDCTGFWVKDKYK 326

  Fly   322 VVDSFNVDRIYLKHKHEGQSQIPDFRHWQIPLGRRFRALKVWITFRTLGAEGLRNHVRKHIELAK 386
            :..:|:|:.|||:|.:.|.:  .||.||||||.||||::|:|...|:.|.:.|:.|||...::||
  Rat   327 LQQTFSVNPIYLRHANSGVA--TDFMHWQIPLSRRFRSIKLWFVIRSFGVKNLQAHVRHGTDMAK 389

  Fly   387 QFEQLVLKDSRFELVAPRALGLVCFRPKGDNEITTQLLQRLMDRKKIYMVKAEHAGRQFLRFVVC 451
            .||.||..|..||:.|.|.||||.||.||.|.:|..:|:.:....:::::.|....:..:||.|.
  Rat   390 YFESLVRSDPVFEIPAERHLGLVVFRLKGPNCLTESVLKEIAKTGQVFLIPATIQDKLIIRFTVT 454

  Fly   452 GMDTKASDIDFAWQEIESQLTDLQAEQSLVARKSGNVGDLAQH 494
            ...|...||...|..|               |::.|: .|:||
  Rat   455 SQFTTKDDILRDWNLI---------------REAANL-VLSQH 481

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
amd	NP_476592.1	Pyridoxal_deC	35..414	CDD:395219	187/379 (49%)
Hdc	NP_058712.2	Pyridoxal_deC	39..417	CDD:395219	187/379 (49%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	481..502		1/1 (100%)