Protein Alignment amd and hdl-2

DIOPT Version :9

• Sequence 1: NP_476592.1
• Gene: amd / 35188
• FlyBaseID: FBgn0000075
• Length: 510
• Species: Drosophila melanogaster
• Sequence 2: NP_501539.3
• Gene: hdl-2 / 182464
• WormBaseID: WBGene00006409
• Length: 611
• Species: Caenorhabditis elegans
• Alignment Length: 514
• Identity: 105/514 - (20%)
• Similarity: 193/514 - (37%)
• Gaps: 110/514 - (21%)

  Fly     5 EFREFGKAAIDYIADYLENIRDDDVLPNVEPGYLLDLLPTEMPEEPEAWKDVLGDISRVIKPGLT 69
            ||.:.....:.:|.||.:......|:|  |.......:..::||:.|...::|.|:..::.|.:.
 Worm   118 EFIKCMSLVVQFINDYFDESHKQPVIP--ENDVNSSRIHVKVPEKAEELTEILKDLKEIVIPNIC 180

  Fly    70 HWQSPHMHAYYPTSTSYPSIVGEMLASGFGVIGFSWICSPACTELEVVVMDWLAKFLKLPAHFQH 134
            |...|..||.: ...|...:|...:::   .:|.....||....:|.::..||:..:.:|.
 Worm   181 HTHHPRYHAKF-AGKSLADLVASTISA---ALGHDVNSSPIIESIERIICKWLSTSMAIPQ---- 237

  Fly   135 ASDGPGGGVIQGSASEA-------------VLVAVLAAREQAVANYRESHPELSESEVRGRLVAY 186
                     |:.|..|.             |.::|:   ..|:..:.::......|: ....:.|
 Worm   238 ---------IKSSLGELRDPIGTVFYTPCDVFISVI---RHAIEKFEKTDSGKERSK-NADYIVY 289

  Fly   187 SSDQSNSCIEKAGVLAAMPIRLLPAGEDFVLRGDTLRGA-----IEEDVAAGRIPVICVATLGTT 246
            .||.|...:::..:...:.:|.:...|.   .|..:..|     :|:|:|.|..|::.:|..|:.
 Worm   290 CSDDSQVPLKEPCISCRVKLRKVITDEK---NGSGMTSANLLKQMEKDIARGFTPLVIIANYGSA 351

  Fly   247 GTCAYDDIESLSAVCEEFKVWLHVDAAYAGGAFALEECSDL-RKGLDRVDSLNFNLHKFMLVNFD 310
            ...|.|:|..|..|....|:|||:||:|||       |..| ....:.|.:|...:|.   |:..
 Worm   352 NIAANDEIWDLVTVSRSKKIWLHLDASYAG-------CEWLDSNSRNNVHALISEVHS---VHIT 406

  Fly   311 CSAM----------WLRDANKV-VDSFNVDRIYLKHKHEGQSQIPDFRHWQIPLGRRFRALKVWI 364
            ||::          |  ...|: :|...:  :|.:|                       .:::||
 Worm   407 CSSLFPYSGRISVVW--SCEKLELDGAKI--LYGEH-----------------------PIRLWI 444

  Fly   365 TFRTLGAEGLRNHVRKHIELAKQFEQLVLKDSR-FELVAPRALGLVCF---------RPKGDNEI 419
            ..|..|...:|..|::.|.|...|.:.:...|: ||:......|:..|         |.:..|:|
 Worm   445 LIRLHGIRSIREAVKRKIILGNAFSERMSHHSQLFEMHHTNEHGVTVFQYKNKKIKDRTEDTNKI 509

  Fly   420 TTQLLQRLMDRKKIYMVKAEHAGRQFLRFVV----CG---MDTKASDIDFAWQEIESQL 471
            |:.....|:....:........|:..::.||    |.   ||...|.:..:..|.|..|
 Worm   510 TSMFHNYLVLSSTLKFSIVSFHGKVLIKSVVNYGRCNLSIMDESVSTLVNSVDEFEEAL 568

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
amd	NP_476592.1	Pyridoxal_deC	35..414	CDD:278699	83/418 (20%)
hdl-2	NP_501539.3	AAT_I	125..527	CDD:302748	93/464 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0076
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810