Protein Alignment amd and spl-1

DIOPT Version :10

• Sequence 1: NP_476592.1
• Gene: amd / 35188
• FlyBaseID: FBgn0000075
• Length: 510
• Species: Drosophila melanogaster
• Sequence 2: NP_499913.1
• Gene: spl-1 / 176857
• WormBaseID: WBGene00004981
• Length: 552
• Species: Caenorhabditis elegans
• Alignment Length: 349
• Identity: 64/349 - (18%)
• Similarity: 131/349 - (37%)
• Gaps: 91/349 - (26%)

  Fly   109 PACTELEVVVMDWLAKFLKLPAHFQHASDGPGGGVIQGSASEAVLVAVLAAREQAVANYRESHPE 173
            |...::|       |:.:::..:..:..:...|.|..| .:|::::|..:.|.:|.:...| ||
 Worm   174 PGARKME-------AELIRMVLNLYNGPEDSSGSVTSG-GTESIIMACFSYRNRAHSLGIE-HP- 228

  Fly   174 LSESEVRGRLVAYSSDQSNSCIEKAGVLAAMPIRLLPAGEDFVLRGDTLRGAIEEDVA--AGRIP 236
                      |..:...:::..:||..|..|.:|.:|...|..:....:...|:.:|.  .|..|
 Worm   229 ----------VILACKTAHAAFDKAAHLCGMRLRHVPVDSDNRVDLKEMERLIDSNVCMLVGSAP 283

  Fly   237 VICVATLGTTGTCAYDDIESLSAVCEEFKVWLHVDAAYAGGAFALEECSDLRKGLDRVDSLNFNL 301
            .....|:        |.|..::.:.:::.:.:||||..  |.|.:...:|.
 Worm   284 NFPSGTI--------DPIPEIAKLGKKYGIPVHVDACL--GGFMIPFMNDA-------------- 324

  Fly   302 HKFMLVNFDCSAMWLRDANKVVDSFNVDRIYLKHKH----EGQS-------QIPDFRHWQIP--- 352
             .:::..||.       .|..|.|.:.|    .||:    :|.|       ::..|:::.:.
 Worm   325 -GYLIPVFDF-------RNPGVTSISCD----THKYGCTPKGSSIVMYRSKELHHFQYFSVADWC 377

  Fly   353 ---------LGRRFRA--LKVWITFRTLGAEGLRNHVRKHIELAKQFEQLVLKDSRFELVAPRA- 405
                     .|.|..|  ...|.|..:.|.:   .:||:..::.|....|..|..:.:.:.|..
 Worm   378 GGIYATPTIAGSRAGANTAVAWATLLSFGRD---EYVRRCAQIVKHTRMLAEKIEKIKWIKPYGK 439

  Fly   406 --LGLVCFRPKGDN--EITTQLLQ 425
              :.||.|...|.|  |::.::::
 Worm   440 SDVSLVAFSGNGVNIYEVSDKMMK 463

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
amd	NP_476592.1	Pyridoxal_deC	35..414	CDD:395219	61/334 (18%)
spl-1	NP_499913.1	DOPA_deC_like	138..501	CDD:99743	64/349 (18%)