Protein Alignment amd and Ddc

DIOPT Version :9

• Sequence 1: NP_476592.1
• Gene: amd / 35188
• FlyBaseID: FBgn0000075
• Length: 510
• Species: Drosophila melanogaster
• Sequence 2: NP_001177377.1
• Gene: Ddc / 13195
• MGIID: 94876
• Length: 480
• Species: Mus musculus
• Alignment Length: 479
• Identity: 234/479 - (48%)
• Similarity: 327/479 - (68%)
• Gaps: 1/479 - (0%)

  Fly     1 MDAKEFREFGKAAIDYIADYLENIRDDDVLPNVEPGYLLDLLPTEMPEEPEAWKDVLGDISRVIK 65
            ||::|||..||..:|||||||:.|....|.|:||||||..|:|...|:|||.::|::.||.::|.
Mouse     1 MDSREFRRRGKEMVDYIADYLDGIEGRPVYPDVEPGYLRPLIPATAPQEPETYEDIIKDIEKIIM 65

  Fly    66 PGLTHWQSPHMHAYYPTSTSYPSIVGEMLASGFGVIGFSWICSPACTELEVVVMDWLAKFLKLPA 130
            ||:|||.||:..||:||::|||:::.:||....|.|||||..||||||||.|:||||.|.|:||.
Mouse    66 PGVTHWHSPYFFAYFPTASSYPAMLADMLCGAIGCIGFSWAASPACTELETVMMDWLGKMLELPE 130

  Fly   131 HFQHASDGPGGGVIQGSASEAVLVAVLAAREQAVANYRESHPELSESEVRGRLVAYSSDQSNSCI 195
            .|.....|.||||||||||||.|||:||||.:.:...:.:.||.:::.:..:||||:|||::|.:
Mouse   131 AFLAGRAGEGGGVIQGSASEATLVALLAARTKVIRQLQAASPEFTQAAIMEKLVAYTSDQAHSSV 195

  Fly   196 EKAGVLAAMPIRLLPAGEDFVLRGDTLRGAIEEDVAAGRIPVICVATLGTTGTCAYDDIESLSAV 260
            |:||::..:.::.:|:..:|.:|...||.|:|.|.|||.||...|||||||..|::|::..:..:
Mouse   196 ERAGLIGGIKLKAVPSDGNFSMRASALREALERDKAAGLIPFFVVATLGTTSCCSFDNLLEVGPI 260

  Fly   261 CEEFKVWLHVDAAYAGGAFALEECSDLRKGLDRVDSLNFNLHKFMLVNFDCSAMWLRDANKVVDS 325
            |.:..||||:||||||.||...|...|..|::..||.|||.||::||||||||||::....:..:
Mouse   261 CNQEGVWLHIDAAYAGSAFICPEFRYLLNGVEFADSFNFNPHKWLLVNFDCSAMWVKRRTDLTGA 325

  Fly   326 FNVDRIYLKHKHEGQSQIPDFRHWQIPLGRRFRALKVWITFRTLGAEGLRNHVRKHIELAKQFEQ 390
            ||:|.:||||.|:....|.|:||||||||||||:||:|..||..|.:||:.::|||:||:.:||.
Mouse   326 FNMDPVYLKHSHQDSGFITDYRHWQIPLGRRFRSLKMWFVFRMYGVKGLQAYIRKHVELSHEFES 390

  Fly   391 LVLKDSRFELVAPRALGLVCFRPKGDNEITTQLLQRLMDRKKIYMVKAEHAGRQFLRFVVCGMDT 455
            ||.:|.|||:.....|||||||.||.||:...||||:...|||::|......:..|||.||....
Mouse   391 LVRQDPRFEICTEVILGLVCFRLKGSNELNETLLQRINSAKKIHLVPCRLRDKFVLRFAVCARTV 455

  Fly   456 KASDIDFAWQEIESQLTD-LQAEQ 478
            :::.:..||:.|....:. |:||:
Mouse   456 ESAHVQLAWEHISDLASSVLRAEK 479

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
amd	NP_476592.1	Pyridoxal_deC	35..414	CDD:278699	192/378 (51%)
Ddc	NP_001177377.1	Pyridoxal_deC	35..414	CDD:395219	192/378 (51%)
		2 X approximate tandem repeats	58..178		65/119 (55%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0076
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0.815392	Normalized mean entropy	S2516
OMA	1	1.010	-	-		QHG57772
OrthoDB	1	1.010	-	-		D223497at33208
OrthoFinder	1	1.000	-	-		FOG0000865
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11999
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	6.880