Protein Alignment amd and Tdc2

DIOPT Version :10

• Sequence 1: NP_476592.1
• Gene: amd / 35188
• FlyBaseID: FBgn0000075
• Length: 510
• Species: Drosophila melanogaster
• Sequence 2: XP_308519.3
• Gene: Tdc2 / 1269865
• VectorBaseID: AGAMI1_013508
• Length: 642
• Species: Anopheles gambiae
• Alignment Length: 500
• Identity: 234/500 - (46%)
• Similarity: 313/500 - (62%)
• Gaps: 9/500 - (1%)

  Fly     1 MDAKEFREFGKAAIDYIADYLENIRDDDVLPNVEPGYLLDLLPTEMPEEPEAWKDVLGDISRVIK 65
            ||:||||..|...::||.:|||.:....|.|.||||||...||.|.|||||.|:.::.|:...|.
Mosquito     1 MDSKEFRRRGTEMVEYICNYLETLEQRRVTPCVEPGYLKHQLPDEAPEEPEPWEKIMQDVEDKIM 65

  Fly    66 PGLTHWQSPHMHAYYPTSTSYPSIVGEMLASGFGVIGFSWICSPACTELEVVVMDWLAKFLKLPA 130
            ||:||||.|..|||:|:..|:|||:|:||:.|.|.|||||..||||||||.:|:|||.|.:.||.
Mosquito    66 PGVTHWQHPRFHAYFPSGNSFPSILGDMLSDGIGCIGFSWAASPACTELETIVLDWLGKAIGLPD 130

  Fly   131 HFQHASDGP-GGGVIQGSASEAVLVAVLAAREQAVANYRESHPELSESEVRGRLVAYSSDQSNSC 194
            .|.....|. ||||||.||||.|||.:||||.||:...::.||.:.|..:..:|:||.|.:::||
Mosquito   131 SFLALKPGSRGGGVIQTSASECVLVTMLAARAQAIKYLKQQHPFVEEGHLLSKLMAYCSKEAHSC 195

  Fly   195 IEKAGVLAAMPIRLLPAGEDFVLRGDTLRGAIEEDVAAGRIPVICVATLGTTGTCAYDDIESLSA 259
            :|||.:::.:.:|:|...|...||.|||..|:|||...|.||.....||||||:||:||:..:..
Mosquito   196 VEKAAMISFVKLRILEPDEKCCLRADTLIKAMEEDEQQGLIPFFVSTTLGTTGSCAFDDLAEIGE 260

  Fly   260 VCEEF-KVWLHVDAAYAGGAFALEECSDLRKGLDRVDSLNFNLHKFMLVNFDCSAMWLRDANKVV 323
            ..:.| .|||||||||||.||...|...|.||:...||.|.|.:|::|.|||||.:|:||..::.
Mosquito   261 ALQRFPSVWLHVDAAYAGNAFICPELKYLLKGIQYADSFNTNPNKWLLTNFDCSTLWVRDRIRLT 325

  Fly   324 DSFNVDRIYLKHKHEGQSQIPDFRHWQIPLGRRFRALKVWITFRTLGAEGLRNHVRKHIELAKQF 388
            .:..||.:||:|.:. .|.| |:|||.:||.||||:||:|...|:.|..||:.::|.||||||:|
Mosquito   326 SALVVDPLYLQHGYT-DSAI-DYRHWGVPLSRRFRSLKLWFVLRSYGISGLQAYIRHHIELAKRF 388

  Fly   389 EQLVLKDSRFELVAPRALGLVCFRPKGDNEITTQLLQRLMDRKKIYMVKAEHAGRQFLRFVVCGM 453
            |.|||||||||:.....|||||||.||.:.|..:||..:....|::||.|.......:||.....
Mosquito   389 EALVLKDSRFEVCNEVRLGLVCFRLKGTDRINEKLLSSINASGKLHMVPASVNDTYVIRFCAVAQ 453

  Fly   454 DTKASDIDFAWQEIESQLTDLQAEQSLVARKSGNVGDLAQHFQIH 498
            :.|..|||:||..|    ||. |.:.|...::..|.::....:.|
Mosquito   454 NAKVEDIDYAWDVI----TDF-ASEILEKEQADEVSEIVDRRKTH 493

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
amd	NP_476592.1	Pyridoxal_deC	35..414	CDD:395219	194/380 (51%)
Tdc2	XP_308519.3	Pyridoxal_deC	35..414	CDD:395219	194/380 (51%)