Protein Alignment amd and hdc

DIOPT Version :10

• Sequence 1: NP_476592.1
• Gene: amd / 35188
• FlyBaseID: FBgn0000075
• Length: 510
• Species: Drosophila melanogaster
• Sequence 2: XP_017947930.2
• Gene: hdc / 100497702
• XenbaseID: XB-GENE-979207
• Length: 672
• Species: Xenopus tropicalis
• Alignment Length: 475
• Identity: 224/475 - (47%)
• Similarity: 307/475 - (64%)
• Gaps: 3/475 - (0%)

  Fly     1 MDAKEFREFGKAAIDYIADYLENIRDDDVLPNVEPGYLLDLLPTEMPEEPEAWKDVLGDISRVIK 65
            |:.:|:|:.||..:|||..||..:|:..|.|:|:|||:..|||...|.|.|:|:.:..||..:|.
 Frog    28 MEPEEYRKRGKELVDYICQYLSTVRERRVNPDVQPGYMRALLPDSAPVESESWERIFRDIEDIIM 92

  Fly    66 PGLTHWQSPHMHAYYPTSTSYPSIVGEMLASGFGVIGFSWICSPACTELEVVVMDWLAKFLKLPA 130
            ||:.||||||||||:|..||:||::|:|||.....:||:|..||||||||:.|||||||.|.||.
 Frog    93 PGVVHWQSPHMHAYFPALTSWPSLLGDMLADAINCLGFTWASSPACTELEMNVMDWLAKMLGLPC 157

  Fly   131 HF-QHASDGPGGGVIQGSASEAVLVAVLAAREQAVANYRESHPELSESEVRGRLVAYSSDQSNSC 194
            || .|.....||||:|.:.||:.|:|:||||:..:...:.|.|:..:|::..||:||:|:|::|.
 Frog   158 HFLHHYPSSKGGGVLQSTVSESTLIALLAARKNKILEMKTSEPDSDDSQLNSRLIAYASNQAHSS 222

  Fly   195 IEKAGVLAAMPIRLLPAGEDFVLRGDTLRGAIEEDVAAGRIPVICVATLGTTGTCAYDDIESLSA 259
            :||||:::.:.:|.||..|:|.||||||:.|:|||...|.:||...|||||||.||:|.:..|..
 Frog   223 VEKAGLISLVKVRFLPVDENFCLRGDTLKAAVEEDRKNGLVPVFVCATLGTTGVCAFDYLAELGP 287

  Fly   260 VCEEFKVWLHVDAAYAGGAFALEECSDLRKGLDRVDSLNFNLHKFMLVNFDCSAMWLRDANKVVD 324
            ||...|:|||:||||||.||...|...|..|:|..||..||..|:|:|:|||:|.|::|..|:..
 Frog   288 VCAREKLWLHIDAAYAGTAFLCPEFRTLMNGVDYADSFTFNPSKWMMVHFDCTAFWVKDKYKLQQ 352

  Fly   325 SFNVDRIYLKHKHEGQSQIPDFRHWQIPLGRRFRALKVWITFRTLGAEGLRNHVRKHIELAKQFE 389
            :|:|:.|||:|.:.|.:  .||.||||||.||||:||:|...|:.|.:.|:.|:|...||||.||
 Frog   353 TFSVNPIYLRHANTGAA--TDFMHWQIPLSRRFRSLKLWFVIRSFGVKNLQAHIRHGAELAKYFE 415

  Fly   390 QLVLKDSRFELVAPRALGLVCFRPKGDNEITTQLLQRLMDRKKIYMVKAEHAGRQFLRFVVCGMD 454
            .||..|..||:.|.|.||||.||.||.|.:|.::|..|....|:|:|.|.......:||.|....
 Frog   416 SLVTSDQMFEVPAKRHLGLVVFRLKGPNVLTEEVLAELTKSGKMYLVPATINDELIIRFTVTSQF 480

  Fly   455 TKASDIDFAWQEIESQLTDL 474
            |...||...|..|.....::
 Frog   481 TTRDDILRDWNLIRQSAINI 500

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
amd	NP_476592.1	Pyridoxal_deC	35..414	CDD:395219	192/379 (51%)
hdc	XP_017947930.2	Pyridoxal_deC	62..440	CDD:395219	192/379 (51%)