Protein Alignment amd and gad2

DIOPT Version :10

• Sequence 1: NP_476592.1
• Gene: amd / 35188
• FlyBaseID: FBgn0000075
• Length: 510
• Species: Drosophila melanogaster
• Sequence 2: XP_017950266.1
• Gene: gad2 / 100493806
• XenbaseID: XB-GENE-976598
• Length: 588
• Species: Xenopus tropicalis
• Alignment Length: 515
• Identity: 129/515 - (25%)
• Similarity: 214/515 - (41%)
• Gaps: 88/515 - (17%)

  Fly     9 FGKAAIDYIADYLENI--RDDDVLPNVEPGYLLDLLPTEMPEEPEAWKDVLGDISRVIKPGLTHW 71
            |.:..||.:..|:...  |...|:....|..||.....|:.|:|::...:|.:....:|
 Frog   113 FLQDVIDVLLQYVVQTFDRSTKVIDFHYPNELLQAYNWELSEQPQSLDGILLNCKTTLK------ 171

  Fly    72 QSPHMHAYYPTSTSYPSIVGEMLASGFGVIGFS--WICSPACTE------------LEVVVMDWL 122
                    |...|.:|....: |::|..::|.:  |:.|.|.|.            ||.|.:..:
 Frog   172 --------YAIKTGHPRYFNQ-LSTGLDMVGLAADWLTSTANTNMFTYEIAPVFVLLEYVTLKKM 227

  Fly   123 AKFLKLPAHFQHASDGPGGGVIQGSASEAVLVAVLAAREQAVANYRESHPELSESEVRG--RLVA 185
            .:.:..|.       |.|.|:.....:.:.|.|:|.||       .:..||:.|..:..  ||||
 Frog   228 REMIGWPG-------GSGDGIFSPGGAISNLYAMLIAR-------FKMFPEVKEKGMAALPRLVA 278

  Fly   186 YSSDQSNSCIEKAGVLAAMPIRLLPAGEDFVL------RGDTLRGAIEEDVAA----GRIPVICV 240
            ::|:.|:..::|..  ||:.|     |.|.|:      ||..:...:|..:..    |.:|....
 Frog   279 FTSEHSHFSVKKGA--AALGI-----GTDSVILIKADERGRLIPSDLERRIIEAKQNGYVPFFVS 336

  Fly   241 ATLGTTGTCAYDDIESLSAVCEEFKVWLHVDAAYAGGAFALEECSDLRKGLDRVDSLNFNLHKFM 305
            ||.|||...|:|.:.|::.:|:::::|:|||||:.||.....:......|.||.:|:.:|.||.|
 Frog   337 ATAGTTVYGAFDPLVSIADICKKYRIWMHVDAAWGGGLLMSRKHKWKLNGADRANSVTWNPHKMM 401

  Fly   306 LVNFDCSAMWLRDANKVVDSFNVDRIYL--KHKHEGQSQIPDFRHWQIPLGRRFRALKVWITFRT 368
            .|...|||:.:|:...:.:...:...||  :.||...|.  |.....:..||.....|:|:.:|.
 Frog   402 GVPLQCSALLVREEGLMQNCNQMHASYLFQQDKHYDLSY--DTGDKALQCGRHVDIFKLWLMWRA 464

  Fly   369 LGAEGLRNHVRKHIELAKQFEQLVLKDSRFELV---APRALGLVCF-------RPKGDNE----- 418
            .|..|...|:.|.:||::.....:.....:|:|   .|:... |||       |...|||
 Frog   465 KGTTGFEAHIDKCLELSEYLYNKIKNREGYEMVIEGKPQHTN-VCFWYVPPSLRNMEDNEERMNR 528

  Fly   419 ---ITTQLLQRLMDRKKIYMVKAEHAGR-QFLRFVVCGMDTKASDIDFAWQEIESQLTDL 474
               :...:..|:|:.....:....|..: .|.|.|:........||||..:|||....||
 Frog   529 LSKVAPIIKARMMEYGTTMVSYQPHGDKGNFFRMVISNPAAAHQDIDFLIEEIERLGQDL 588

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
amd	NP_476592.1	Pyridoxal_deC	35..414	CDD:395219	105/416 (25%)
gad2	XP_017950266.1	Pyridoxal_deC	141..512	CDD:395219	104/409 (25%)