Protein Alignment amd and gad3

DIOPT Version :10

• Sequence 1: NP_476592.1
• Gene: amd / 35188
• FlyBaseID: FBgn0000075
• Length: 510
• Species: Drosophila melanogaster
• Sequence 2: NP_001083039.2
• Gene: gad3 / 100038790
• ZFINID: ZDB-GENE-070424-80
• Length: 546
• Species: Danio rerio
• Alignment Length: 527
• Identity: 130/527 - (24%)
• Similarity: 210/527 - (39%)
• Gaps: 113/527 - (21%)

  Fly     8 EFGKAAIDYIADYLENI----------RDDDVLPNVEPGYL---LDLLPTEMPEEPEAWKDVLGD 59
            |.|:.|..:....|.||          |...||....|..|   |:....|:|::|:..:.:|.|
Zfish    59 EDGEEATKHFLQELVNILLAYISKSLKRSTKVLDFHYPHQLNEGLEGFSLELPDQPDNLEQLLVD 123

  Fly    60 ISRVIKPGLTHWQSPHMHAYYPTSTSYP--SIVGEMLASGFGVIGFSWICSPACTELEVVVMDWL 122
            ....:|.|:   ::.|...:...||...  .:.||.|.|......|::..||....:|.||:..:
Zfish   124 CRDTLKYGV---KTGHPRFFNQLSTGLDIVGLAGEWLTSTANTNMFTYEISPVFILMEEVVLRKM 185

  Fly   123 AKFLKLPAHFQHASDG---PGGGVIQGSASEAVLVAVLAAREQ---AVANYRESH-----PELSE 176
            ...:..|   :...||   |||       |.:.|.:||.||..   ||    ::|     |
Zfish   186 HTIIGWP---EEDGDGIFCPGG-------SMSNLYSVLLARFHLFPAV----KTHGMCAIP---- 232

  Fly   177 SEVRGRLVAYSSDQSNSCIEKAGVLAAMPIRLLPAGEDFVL------RG----DTLRGAIEEDVA 231
                 ||..::|..|:..|:|:..       :|..|.:.|:      ||    ..|..:|||..:
Zfish   233 -----RLAMFTSAHSHYSIKKSAA-------VLGIGTENVIVVRCDERGKMISSELNSSIEEAKS 285

  Fly   232 AGRIPVICVATLGTTGTCAYDDIESLSAVCEEFKVWLHVDAAYAGGAFALEECSDLRKGLDRVDS 296
            .|.:|....||.|||...|:|.:..::.:||...:|:|||||:.||.....:......|::|..|
Zfish   286 KGLVPFYVNATAGTTVYGAFDPLHKIADICEHHGLWMHVDAAWGGGLLLSNKHRVKLHGIERAHS 350

  Fly   297 LNFNLHKFMLVNFDCSAM------WLRDANKVVDSFNVDRIYLKHKHEGQSQIPDFRHWQIPLGR 355
            :.:|.||.|.|...||.:      .|:..|::...:    ::...||...|.  |.....|..||
Zfish   351 VTWNPHKMMGVPLQCSTILVKRKGLLQQCNQLCAEY----LFQPDKHYEVSY--DTGDKSIQCGR 409

  Fly   356 RFRALKVWITFRTLGAEGLRNHVRKHIELAKQFEQLVLKDSRFELVAPRALGLVCFRPKGDNEIT 420
            .....|:|:.::..|:||..:.|...:|.|:.....:.:.:.|:||...       :|:..|...
Zfish   410 HVDIFKLWLMWKAKGSEGFESQVNHCLENAEYLYYKLKRRTDFQLVFKG-------KPEHSNVCF 467

  Fly   421 TQLLQRLMD-------RKKIYMVKAE-----------HAGRQ-------FLRFVVCGMDTKASDI 460
            ..|.:|:.:       .|:::||..:           ..|.|       |.|.|.....|:..|:
Zfish   468 WYLPKRVQNIPLGPEREKELHMVAPKIKTKMMEEGFTMIGYQPLEDKVNFFRCVFSNPATQREDV 532

  Fly   461 DFAWQEI 467
            ||...||
Zfish   533 DFLLDEI 539

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
amd	NP_476592.1	Pyridoxal_deC	35..414	CDD:395219	103/410 (25%)
gad3	NP_001083039.2	Pyridoxal_deC	96..469	CDD:395219	105/418 (25%)