DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Lim3 and zfhx2

DIOPT Version :9

Sequence 1:	NP_001260559.1	Gene:	Lim3 / 35184	FlyBaseID:	FBgn0002023	Length:	555	Species:	Drosophila melanogaster
Sequence 2:	XP_001335082.5	Gene:	zfhx2 / 795005	ZFINID:	ZDB-GENE-030131-6699	Length:	1529	Species:	Danio rerio

Alignment Length:	270	Identity:	67/270 - (24%)
Similarity:	100/270 - (37%)	Gaps:	95/270 - (35%)

- Green bases have known domain annotations that are detailed below.

  Fly   257 KRPRTTITAKQLETLKTAYNNSPKPARHVREQLSQDTGLDMRVVQVWFQNRRAKEKRLKKDAGRT 321
            :||||.:|:.||..|::.|.....|.....|.:..:.||.::|||:||||.|||||
Zfish  1341 RRPRTHLTSLQLSILQSCYETCAHPNALECEAVGTELGLPLKVVQIWFQNTRAKEK--------- 1396

  Fly   322 RWSQYFRSMKGNCSPRTDKFLDKDELKVDYDSFSHHDLSNDSYSTVN-LGLDEGASPHSIRGSYM 385
            ||......|..|.|..:.|.                |:|:.||...| |..:....|..::.:.:
Zfish  1397 RWRLQQEKMSPNPSDPSKKI----------------DVSSGSYLQYNALRANRPILPKPVQLTVV 1445

  Fly   386 HGSSSPSQYPPSSRSPPPVGQGHTFGSYPDNIVYTNIDQ-------AVGSSLHASKAHHRLH--S 441
                          .|.|        ||  ||..|.:.:       |.|:... |:|..|.|  |
Zfish  1446 --------------DPAP--------SY--NIGQTTVRETLIGKCDACGAEFE-SRAAARDHVFS 1485

  Fly   442 SNNVSDLSNDSSPDQGYPDFPPSPDSWLGDSGSTNTTSANNNANNNSSSSHNNNNSSGGGSGG-V 505
            :.:::.|                           .||:....|:..|       |.||.||.| :
Zfish  1486 ARHLATL---------------------------RTTNFGLQASMVS-------NGSGTGSVGII 1516

  Fly   506 SVSTAPNPSA 515
            |.|:.|:|::
Zfish  1517 SQSSTPSPAS 1526

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Lim3	NP_001260559.1	LIM1_Lhx3_Lhx4	122..173	CDD:188754
		LIM2_Lhx3_Lhx4	181..236	CDD:188762
		Homeobox	259..312	CDD:278475	22/52 (42%)
zfhx2	XP_001335082.5	C2H2 Zn finger	171..193	CDD:275368
		C2H2 Zn finger	223..241	CDD:275368
		Homeobox	1039..1090	CDD:278475
		HOX	1340..1396	CDD:197696	23/54 (43%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1174754at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.010