Protein Alignment Lim3 and Lmx1a

DIOPT Version :9

• Sequence 1: NP_001260559.1
• Gene: Lim3 / 35184
• FlyBaseID: FBgn0002023
• Length: 555
• Species: Drosophila melanogaster
• Sequence 2: NP_729801.1
• Gene: Lmx1a / 39406
• FlyBaseID: FBgn0052105
• Length: 640
• Species: Drosophila melanogaster
• Alignment Length: 630
• Identity: 175/630 - (27%)
• Similarity: 236/630 - (37%)
• Gaps: 231/630 - (36%)

  Fly    14 HHQHQHQLQHPPQQQPHPHQQLQHPLQQQQHLSAMDNHQQHQPHIHQQQQQQQQLP------PTP 72
            |.|||.| || .|||.|||||                |||     ||||......|      |||
  Fly    76 HQQHQQQ-QH-QQQQQHPHQQ----------------HQQ-----HQQQHAASTTPVPINSCPTP 117

  Fly    73 QASHLVGGQQQQQQHPHHN------------HLAVDQ--------------DDPNPE-------- 103
            .....:........|.::|            |.|.:.              ..|:|.
  Fly   118 TGHSPLSSSSSNSNHNNNNNNNNGGSSSNNLHSACNTLTAAAVAAASAAAVAAPSPAGTSVATSQ 182

  Fly   104 ---LVLALI--SRNRALEATIPK------------------------------------------ 121
               .|.|.|  :...|..||.|.
  Fly   183 LGGAVAAAIAAAAAAAAAATTPTSTGPAATGSGNANGSGNGNGNGNGNGNGNGNGNGGGAATASA 247

  Fly   122 ---------------------------CGGCHELILDRFILKVLERTWHAKCLQCSECHGQLNDK 159
                                       |.||.:.|.|||::.|.:..||.:||.|..|..||:..
  Fly   248 AAASKLSADCSGRTEVGHIKCEKNFELCEGCGQKIHDRFLMNVGDANWHEQCLACCYCGMQLHHT 312

  Fly   160 CFARNGQLFCKEDFFKRYGTKCSACDMGIPPTQVVRRAQDN-VYHLQCFLCAMCSRTLNTGDEFY 223
            |:.||.:|:||.|:.:.:|.|||:|...|.|.::|.|...| |:||.||:|..|...|..|::|
  Fly   313 CYVRNSKLYCKMDYDRLFGVKCSSCCHAILPQELVMRPIPNFVFHLPCFVCYACRLPLQKGEQF- 376

  Fly   224 LMEDRKLICKR-DYEE------AKAK-----GLYLDGSL---DGDQPNKRPRTTITAKQLETLKT 273
            ::.|.:|.|.| |.|:      |.|:     ||..:..|   ||.:..|||||.:|::|.:..|.
  Fly   377 MLRDGQLFCYRHDLEKEMFLAAAAAQHCGFVGLDEEDLLRPRDGRRGPKRPRTILTSQQRKQFKA 441

  Fly   274 AYNNSPKPARHVREQLSQDTGLDMRVVQVWFQNRRAKEKRL----KKDAGRTRWSQYFRSMKGNC 334
            :::.||||.|.|||.|::||||.:|||||||||:|||.|::    |::.|....|...|. .||.
  Fly   442 SFDQSPKPCRKVREALAKDTGLSVRVVQVWFQNQRAKMKKIQRKAKQNGGSGGGSGSGRG-TGNS 505

  Fly   335 SPRTDKFLDKDELKVDYDSFSHHDLSNDSYSTVNLGLDEGASPHSIRGSYMHGSSSPSQYPPSSR 399
            |...||..:..|     |.....:|..||                  ..|:.|..|
  Fly   506 SATDDKDTNDKE-----DKCVKQELGGDS------------------SGYLGGLDS--------- 538

  Fly   400 SPPPVGQGHTFGSYP--DNIVYTNIDQAVGSSLHASKAHHRLHSSNNVSDLSNDSSPDQGYPDFP 462
                     ||.|.|  .|:.::..|....|           :.|...||||.|.|      :|.
  Fly   539 ---------TFASQPLNPNLPFSPDDYPANS-----------NDSFCSSDLSLDGS------NFD 577

  Fly   463 PSPDSWLGDSGSTN------TTSANNNANNNSSSSH----NNNNS 497
            ...|.  .||.|.|      |:|:.|..:::.|:.|    |.|||
  Fly   578 QLDDD--ADSLSLNNLELQSTSSSGNQHSHSHSNPHDMLANLNNS 620

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Lim3	NP_001260559.1	LIM1_Lhx3_Lhx4	122..173	CDD:188754	22/50 (44%)
		LIM2_Lhx3_Lhx4	181..236	CDD:188762	22/56 (39%)
		Homeobox	259..312	CDD:278475	31/52 (60%)
Lmx1a	NP_729801.1	LIM1_Lmx1b	275..327	CDD:188757	23/51 (45%)
		LIM	333..388	CDD:295319	22/55 (40%)
		Homeobox	427..480	CDD:278475	31/52 (60%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45444992
Domainoid	1	1.000	47	0.796	Domainoid score	I4515
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24208
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.940