Protein Alignment Lim3 and Lhx4

DIOPT Version :10

• Sequence 1: NP_001260559.1
• Gene: Lim3 / 35184
• FlyBaseID: FBgn0002023
• Length: 555
• Species: Drosophila melanogaster
• Sequence 2: NP_001101818.2
• Gene: Lhx4 / 360858
• RGDID: 1308044
• Length: 390
• Species: Rattus norvegicus
• Alignment Length: 384
• Identity: 195/384 - (50%)
• Similarity: 236/384 - (61%)
• Gaps: 57/384 - (14%)

  Fly   119 IPKCGGCHELILDRFILKVLERTWHAKCLQCSECHGQLNDKCFARNGQLFCKEDFFKRYGTKCSA 183
            ||:|.||::.|||:||||||:|.||:.||:|::|..||.|:||:|.|.::||||||||:||||:|
  Rat    27 IPQCAGCNQHILDKFILKVLDRHWHSSCLKCADCQMQLADRCFSRAGSVYCKEDFFKRFGTKCTA 91

  Fly   184 CDMGIPPTQVVRRAQDNVYHLQCFLCAMCSRTLNTGDEFYLMEDRKLICKRDYEEAKAKGLYLDG 248
            |..|||||||||:|||.||||.||.|.:|:|.|.||||||||||.:|:||.|||.||...
  Rat    92 CQQGIPPTQVVRKAQDFVYHLHCFACIICNRQLATGDEFYLMEDGRLVCKEDYETAKQND----- 151

  Fly   249 SLDGDQPNKRPRTTITAKQLETLKTAYNNSPKPARHVREQLSQDTGLDMRVVQVWFQNRRAKEKR 313
              |.:...||||||||||||||||.||.||||||||||||||.:|||||||||||||||||||||
  Rat   152 --DSEAGAKRPRTTITAKQLETLKNAYKNSPKPARHVREQLSSETGLDMRVVQVWFQNRRAKEKR 214

  Fly   314 LKKDAGRTRWSQYFRSMK---------------------GNCSPRTDKFLDK----DELKVDYDS 353
            |||||||.||.|:::|:|                     ...|.|.|:.|.:    :.:..:...
  Rat   215 LKKDAGRHRWGQFYKSVKRSRGGSKQEKESSAEDCGVSDSELSFREDQILSELGHTNRIYGNVGD 279

  Fly   354 FSHHDLSNDSYSTVNLG-----LDEGASPHSIRGSYMHGSSSPSQYPPSSRSPPPVGQGHTFGSY 413
            .:...|.|.|:|....|     |.:| ||:.|..|....||.||..|..|      |..:|..|
  Rat   280 VTGGQLMNGSFSMDGTGQSYQDLRDG-SPYGIPQSPSSISSLPSHAPLLS------GLDYTVDS- 336

  Fly   414 PDNI-VYTNIDQAVGSSLHASKAHHRLHSSNNVSDLSNDSSPDQGYPDFPPSPDSWLGD 471
              |: |..:..|.|..:|.|.       :....||||..||  .||||||.||.|||.:
  Rat   337 --NLGVIAHPGQGVSQTLRAM-------AGGPTSDLSTGSS--VGYPDFPTSPASWLDE 384

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Lim3	NP_001260559.1	LIM1_Lhx3_Lhx4	122..173	CDD:188754	29/50 (58%)
		LIM2_Lhx3_Lhx4	181..236	CDD:188762	38/54 (70%)
		Homeodomain	257..313	CDD:459649	51/55 (93%)
Lhx4	NP_001101818.2	LIM1_Lhx4	30..81	CDD:188852	29/50 (58%)
		LIM2_Lhx3_Lhx4	89..144	CDD:188762	38/54 (70%)
		Homeodomain	158..214	CDD:459649	51/55 (93%)