Protein Alignment Lim3 and Lmx1a

DIOPT Version :10

• Sequence 1: NP_001260559.1
• Gene: Lim3 / 35184
• FlyBaseID: FBgn0002023
• Length: 555
• Species: Drosophila melanogaster
• Sequence 2: NP_001099437.2
• Gene: Lmx1a / 289201
• RGDID: 1304784
• Length: 382
• Species: Rattus norvegicus
• Alignment Length: 325
• Identity: 113/325 - (34%)
• Similarity: 151/325 - (46%)
• Gaps: 74/325 - (22%)

  Fly   117 ATIPK--CGGCHELILDRFILKVLERTWHAKCLQCSECHGQLNDKCFARNGQLFCKEDFFKRYGT 179
            |..||  |.||..:|.|||:|::.:..||.:|:||:.|...|...||.|:.:|:||..:.|.:..
  Rat    28 AVSPKSVCEGCQRVISDRFLLRLNDSFWHEQCVQCASCKEPLETTCFYRDKKLYCKYHYEKLFAV 92

  Fly   180 KCSACDMGIPPTQVVRRAQDNVYHLQCFLCAMCSRTLNTGDEFYLMEDRKLICKRDYEEAK---- 240
            ||..|...|.|.:.|.|||.:||||.||.|.:|.|.|..||||.|.|. :|:||.|||:.:
  Rat    93 KCGGCFEAIAPNEFVMRAQKSVYHLSCFCCCVCERQLQKGDEFVLKEG-QLLCKGDYEKERELLS 156

  Fly   241 -------------------------AKGLYLDGSLDGDQPNKRPRTTITAKQLETLKTAYNNSPK 280
                                     .||...||. |..:| |||||.:|.:|....|.::..|.|
  Rat   157 LVSPAASDSGKSDDEESLCKSAHGAGKGASEDGK-DHKRP-KRPRTILTTQQRRAFKASFEVSSK 219

  Fly   281 PARHVREQLSQDTGLDMRVVQVWFQNRRAKEKRL-------KKDAGRT-RWSQYFRSMKGNCS-- 335
            |.|.|||.|:.:|||.:|||||||||:|||.|:|       ::|...| |.|....:..||..
  Rat   220 PCRKVRETLAAETGLSVRVVQVWFQNQRAKMKKLARRQQQQQQDQQNTQRLSSAQTNGSGNAGME 284

  Fly   336 ---------PRTDKFLDKDELKVDYDSFSH---------------------HDLSNDSYSTVNLG 370
                     |...:.|..::...:.|.|..                     |||.:|..|..|||
  Rat   285 GIMNPYTTLPTPQQLLAIEQSVYNSDPFRQGLTPPQMPGDHMHPYGAEPLFHDLDSDDTSLSNLG 349

  Fly   371  370
              Rat   350  349

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Lim3	NP_001260559.1	LIM1_Lhx3_Lhx4	122..173	CDD:188754	21/50 (42%)
		LIM2_Lhx3_Lhx4	181..236	CDD:188762	27/54 (50%)
		Homeodomain	257..313	CDD:459649	31/55 (56%)
Lmx1a	NP_001099437.2	LIM1_Lmx1a	35..86	CDD:188756	21/50 (42%)
		LIM2_Lmx1a_Lmx1b	94..148	CDD:188764	27/54 (50%)
		Homeodomain	196..252	CDD:459649	31/55 (56%)