DRSC/TRiP Functional Genomics Resources

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Protein Alignment Lim3 and Lmx1b

DIOPT Version :9

Sequence 1:NP_001260559.1 Gene:Lim3 / 35184 FlyBaseID:FBgn0002023 Length:555 Species:Drosophila melanogaster
Sequence 2:XP_006497809.1 Gene:Lmx1b / 16917 MGIID:1100513 Length:408 Species:Mus musculus


Alignment Length:412 Identity:124/412 - (30%)
Similarity:169/412 - (41%) Gaps:132/412 - (32%)


- Green bases have known domain annotations that are detailed below.


  Fly   122 CGGCHELILDRFILKVLERTWHAKCLQCSECHGQLNDKCFARNGQLFCKEDFFKRYGTKCSACDM 186
            |.||...|.|||:::|.|.:||.:||||:.|...|...|:.|:.:|:||:|:.:.:..|||.|..
Mouse    62 CEGCQRPISDRFLMRVNESSWHEECLQCAACQQALTTSCYFRDRKLYCKQDYQQLFAAKCSGCME 126

  Fly   187 GIPPTQVVRRAQDNVYHLQCFLCAMCSRTLNTGDEFYLMEDRKLICKRDYEE------------- 238
            .|.||:.|.||.:.||||.||.|.:|.|.|..||||.|.|. :|:||.|||:             
Mouse   127 KIAPTEFVMRALECVYHLGCFCCCVCERQLRKGDEFVLKEG-QLLCKGDYEKEKDLLSSVSPDES 190

  Fly   239 --------------AKAKGLYLDGS-LDGDQPN--KRPRTTITAKQLETLKTAYNNSPKPARHVR 286
                          ||.:|....|| .||..|.  |||||.:|.:|....|.::..|.||.|.||
Mouse   191 DSVKSEDEDGDMKPAKGQGSQSKGSGDDGKDPRRPKRPRTILTTQQRRAFKASFEVSSKPCRKVR 255

  Fly   287 EQLSQDTGLDMRVVQVWFQNRRAKEKRLKKDAGRTRWSQYFRSMKGNCSPRTDKFLDKDELKVDY 351
            |.|:.:|||.:|||||||||:|||.|:|.:                                   
Mouse   256 ETLAAETGLSVRVVQVWFQNQRAKMKKLAR----------------------------------- 285

  Fly   352 DSFSHHDLSNDSYSTVNLGLDEGASPHSIRGSYMHG---SSSP-----------SQYPPSSRSP- 401
                .|....:..::..||       ..:..|.|.|   |.:|           .|.|..|..| 
Mouse   286 ----RHQQQQEQQNSQRLG-------QEVLSSRMEGMMASYTPLAPPQQQIVAMEQSPYGSSDPF 339

  Fly   402 -----PPVGQGHTFGSYPDNIVYTNIDQAVGSSLHASKAHHRLHSSNNVSDLSNDSSPDQGYPDF 461
                 ||...|.....|.::.::.:||                 |..:::.||            
Mouse   340 QQGLTPPQMPGDHMNPYGNDSIFHDID-----------------SDTSLTSLS------------ 375

  Fly   462 PPSPDSWLG--DSGSTNTTSAN 481
                |.:||  |.||......|
Mouse   376 ----DCFLGSSDVGSLQARVGN 393

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Lim3NP_001260559.1 LIM1_Lhx3_Lhx4 122..173 CDD:188754 22/50 (44%)
LIM2_Lhx3_Lhx4 181..236 CDD:188762 28/54 (52%)
Homeobox 259..312 CDD:278475 29/52 (56%)
Lmx1bXP_006497809.1 LIM1_Lmx1b 62..114 CDD:188757 23/51 (45%)
LIM2_Lmx1a_Lmx1b 121..175 CDD:188764 28/54 (52%)
Homeobox 228..282 CDD:365835 29/53 (55%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

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