DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment Lim3 and Lhx9

DIOPT Version :9

Sequence 1:NP_001260559.1 Gene:Lim3 / 35184 FlyBaseID:FBgn0002023 Length:555 Species:Drosophila melanogaster
Sequence 2:NP_001036042.1 Gene:Lhx9 / 16876 MGIID:1316721 Length:397 Species:Mus musculus


Alignment Length:342 Identity:107/342 - (31%)
Similarity:160/342 - (46%) Gaps:92/342 - (26%)


- Green bases have known domain annotations that are detailed below.


  Fly   122 CGGCHELILDRFILKVLERTWHAKCLQCSECHGQLNDK--CFARNGQLFCKEDFFKRYGT-KCSA 183
            |.||...|.||:.|..:::.||.:||:|.||...|..:  |||::|.::||||:::|:.. :|:.
Mouse    71 CAGCGGKISDRYYLLAVDKQWHLRCLKCCECKLALESELTCFAKDGSIYCKEDYYRRFSVQRCAR 135

  Fly   184 CDMGIPPTQVVRRAQDNVYHLQCFLCAMCSRTLNTGDEFYLMEDRKLICKRDYE----------- 237
            |.:||..:::|.||:|:||||.||.|:.|::||.|||.|. |:|..:.|:..:|           
Mouse   136 CHLGISASEMVMRARDSVYHLSCFTCSTCNKTLTTGDHFG-MKDSLVYCRAHFETLLQGEYPPQL 199

  Fly   238 -----EAKAKGL---YLDGS----------------------------------LDGD------- 253
                 .||:.||   |.:|:                                  ||.|       
Mouse   200 SYTELAAKSGGLALPYFNGTGTVQKGRPRKRKSPALGVDIVNYNSGCNENEADHLDRDQQPYPPS 264

  Fly   254 QPNKRPRTTITAKQLETLKT--AYNNSPKPARHVREQLSQDTGLDMRVVQVWFQNRRAKEKR--L 314
            |..||.||:....||.|:|:  |.|::| .|:.:: ||:|.|||..||:||||||.|||.:|  |
Mouse   265 QKTKRMRTSFKHHQLRTMKSYFAINHNP-DAKDLK-QLAQKTGLTKRVLQVWFQNARAKFRRNLL 327

  Fly   315 KKDAGRTRWSQYFRSMKGNCSPRTDKFLDKDELKVDYDSFSHHDLSNDS---YSTVNLGLDEGAS 376
            :::.|..      ....|...|.... .|...|.....:.:..||:|.:   .:||...:|.   
Mouse   328 RQENGGV------DKADGTSLPAPPS-ADSGALTPPGTATTLTDLTNPTVTVVTTVTSNMDS--- 382

  Fly   377 PHSIRGSYMHGSSSPSQ 393
                     |...||||
Mouse   383 ---------HEPGSPSQ 390

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Lim3NP_001260559.1 LIM1_Lhx3_Lhx4 122..173 CDD:188754 22/52 (42%)
LIM2_Lhx3_Lhx4 181..236 CDD:188762 25/54 (46%)
Homeobox 259..312 CDD:278475 27/54 (50%)
Lhx9NP_001036042.1 LIM1_Lhx2 61..124 CDD:188853 22/52 (42%)
LIM2_Lhx2_Lhx9 129..187 CDD:188763 25/58 (43%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 248..272 6/23 (26%)
Homeobox 271..323 CDD:278475 27/53 (51%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 330..365 5/41 (12%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 378..397 6/25 (24%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

Return to query results.
Submit another query.