Protein Alignment Lim3 and Lhx5

DIOPT Version :10

• Sequence 1: NP_001260559.1
• Gene: Lim3 / 35184
• FlyBaseID: FBgn0002023
• Length: 555
• Species: Drosophila melanogaster
• Sequence 2: NP_032525.1
• Gene: Lhx5 / 16873
• MGIID: 107792
• Length: 402
• Species: Mus musculus
• Alignment Length: 437
• Identity: 151/437 - (34%)
• Similarity: 212/437 - (48%)
• Gaps: 110/437 - (25%)

  Fly   122 CGGCHELILDRFILKVLERTWHAKCLQCSECHGQLNDKCFARNGQLFCKEDFFKRYGTKCSACDM 186
            |.||...|||||:|.||:|.||.||:||.||...|::|||:|.|:|:||.|||:|:||||:.|..
Mouse     5 CAGCERPILDRFLLNVLDRAWHIKCVQCCECKTNLSEKCFSREGKLYCKNDFFRRFGTKCAGCAQ 69

  Fly   187 GIPPTQVVRRAQDNVYHLQCFLCAMCSRTLNTGDEFYLMEDRKLICKRDYEEAKAKGLYLDGSLD 251
            ||.|:.:||:|:..|:||.||.|.:|::.|:||:|.|::::.|.:||.||..:.:   ..:|||:
Mouse    70 GISPSDLVRKARSKVFHLNCFTCMVCNKQLSTGEELYVIDENKFVCKDDYLSSSS---LKEGSLN 131

  Fly   252 G------------------DQP------------------------NKR--PRTTITAKQLETLK 272
            .                  |.|                        .||  |||||.||||||||
Mouse   132 SVSSCTDRSLSPDLQDPLQDDPKETDNSTSSDKETANNENEEQNSGTKRRGPRTTIKAKQLETLK 196

  Fly   273 TAYNNSPKPARHVREQLSQDTGLDMRVVQVWFQNRRAKEKRLKK-DAGRTRWSQYFRSMKGNCSP 336
            .|:..:|||.||:||||:|:|||:|||:||||||||:||:|:|: .|...|...:||      ||
Mouse   197 AAFAATPKPTRHIREQLAQETGLNMRVIQVWFQNRRSKERRMKQLSALGARRHAFFR------SP 255

  Fly   337 RTDK----FLDKDELKVDYDSFSHHDLSNDSYSTVNLGLDEGASPHSIRGSYMHGSSSPSQYPPS 397
            |..:    .||:.|:........:.|..:|.|           :|......:.||..|.:|.|..
Mouse   256 RRMRPLGGRLDESEMLGSTPYTYYGDYQSDYY-----------APGGNYDFFAHGPPSQAQSPAD 309

  Fly   398 SRSPPPVGQGHT-FGSYPDNIVYTNIDQAVGSSLHASKAHHRLHSSNN--VSDL---SNDSSPDQ 456
            |......|.|.| .|:....:...                   |.::|  .:|:   .:..||:.
Mouse   310 SSFLAASGPGSTPLGALEPPLAGP-------------------HGADNPRFTDMISHPDTPSPEP 355

  Fly   457 GYP--------------DFPPSPDSWLGDSGSTNTTSANNNANNNSS 489
            |.|              ..||.|.|  |.||.:...|..|...|.::
Mouse   356 GLPGALHPMPGEVFSGGPSPPFPMS--GTSGYSGPLSHPNPELNEAA 400

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Lim3	NP_001260559.1	LIM1_Lhx3_Lhx4	122..173	CDD:188754	29/50 (58%)
		LIM2_Lhx3_Lhx4	181..236	CDD:188762	23/54 (43%)
		Homeodomain	257..313	CDD:459649	42/57 (74%)
Lhx5	NP_032525.1	LIM1_Lhx1_Lhx5	5..56	CDD:188753	29/50 (58%)
		LIM2_Lhx1_Lhx5	64..119	CDD:188761	23/54 (43%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	124..186		9/64 (14%)
		Homeodomain	181..237	CDD:459649	40/55 (73%)
		PHA03378	<247..>392	CDD:223065	38/182 (21%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	298..402		27/124 (22%)