DRSC/TRiP Functional Genomics Resources

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Protein Alignment Lim3 and Lmx1b

DIOPT Version :9

Sequence 1:NP_001260559.1 Gene:Lim3 / 35184 FlyBaseID:FBgn0002023 Length:555 Species:Drosophila melanogaster
Sequence 2:NP_446161.1 Gene:Lmx1b / 114501 RGDID:620843 Length:402 Species:Rattus norvegicus


Alignment Length:412 Identity:124/412 - (30%)
Similarity:169/412 - (41%) Gaps:132/412 - (32%)


- Green bases have known domain annotations that are detailed below.


  Fly   122 CGGCHELILDRFILKVLERTWHAKCLQCSECHGQLNDKCFARNGQLFCKEDFFKRYGTKCSACDM 186
            |.||...|.|||:::|.|.:||.:||||:.|...|...|:.|:.:|:||:|:.:.:..|||.|..
  Rat    56 CEGCQRPISDRFLMRVNESSWHEECLQCAACQQALTTSCYFRDRKLYCKQDYQQLFAAKCSGCME 120

  Fly   187 GIPPTQVVRRAQDNVYHLQCFLCAMCSRTLNTGDEFYLMEDRKLICKRDYEE------------- 238
            .|.||:.|.||.:.||||.||.|.:|.|.|..||||.|.|. :|:||.|||:             
  Rat   121 KIAPTEFVMRALECVYHLGCFCCCVCERQLRKGDEFVLKEG-QLLCKGDYEKEKDLLSSVSPDES 184

  Fly   239 --------------AKAKGLYLDGS-LDGDQPN--KRPRTTITAKQLETLKTAYNNSPKPARHVR 286
                          ||.:|....|| .||..|.  |||||.:|.:|....|.::..|.||.|.||
  Rat   185 DSVKSEDEDGDMKPAKGQGSQNKGSGDDGKDPRRPKRPRTILTTQQRRAFKASFEVSSKPCRKVR 249

  Fly   287 EQLSQDTGLDMRVVQVWFQNRRAKEKRLKKDAGRTRWSQYFRSMKGNCSPRTDKFLDKDELKVDY 351
            |.|:.:|||.:|||||||||:|||.|:|.:                                   
  Rat   250 ETLAAETGLSVRVVQVWFQNQRAKMKKLAR----------------------------------- 279

  Fly   352 DSFSHHDLSNDSYSTVNLGLDEGASPHSIRGSYMHG---SSSP-----------SQYPPSSRSP- 401
                .|....:..::..||       ..:..|.|.|   |.:|           .|.|..|..| 
  Rat   280 ----RHQQQQEQQNSQRLG-------QEVLSSRMEGMMASYTPLAPPQQQIVAMEQSPYGSSDPF 333

  Fly   402 -----PPVGQGHTFGSYPDNIVYTNIDQAVGSSLHASKAHHRLHSSNNVSDLSNDSSPDQGYPDF 461
                 ||...|.....|.::.::.:||                 |..:::.||            
  Rat   334 QQGLTPPQMPGDHMNPYGNDSIFHDID-----------------SDTSLTSLS------------ 369

  Fly   462 PPSPDSWLG--DSGSTNTTSAN 481
                |.:||  |.||......|
  Rat   370 ----DCFLGSSDVGSLQARVGN 387

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Lim3NP_001260559.1 LIM1_Lhx3_Lhx4 122..173 CDD:188754 22/50 (44%)
LIM2_Lhx3_Lhx4 181..236 CDD:188762 28/54 (52%)
Homeobox 259..312 CDD:278475 29/52 (56%)
Lmx1bNP_446161.1 LIM1_Lmx1b 56..108 CDD:188757 23/51 (45%)
LIM2_Lmx1a_Lmx1b 115..169 CDD:188764 28/54 (52%)
Homeobox 222..276 CDD:395001 29/53 (55%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
21.910

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