DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10700 and TRR2

DIOPT Version :9

Sequence 1:	NP_609942.1	Gene:	CG10700 / 35183	FlyBaseID:	FBgn0032754	Length:	539	Species:	Drosophila melanogaster
Sequence 2:	NP_011974.1	Gene:	TRR2 / 856506	SGDID:	S000001148	Length:	342	Species:	Saccharomyces cerevisiae

Alignment Length:	385	Identity:	72/385 - (18%)
Similarity:	133/385 - (34%)	Gaps:	131/385 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly    80 TGDIENFPGL-DSLPCHRVNVDSRGQVLVQVKRSYLLRHARIKSMACRNWQDQRHFVVVGGGPSG 143
            |.|||||||. :||                                                 ||
Yeast    72 TTDIENFPGFPESL-------------------------------------------------SG 87

  Fly   144 AVCVETLRQEGFTGRLTLVCGEKHLPYDRTRIMNLLNTYTKNLALREEQFYKDYGIEMQLGVSAE 208
            :..:|.:|::.......::          |..::.::..:|...|..| |.:|          ||
Yeast    88 SELMERMRKQSAKFGTNII----------TETVSKVDLSSKPFRLWTE-FNED----------AE 131

  Fly   209 RLDTNCNTLHCTNGKTFPYDKIYIATGYSAVTPNIPGVHL---KNVKVIRNIGDARSIFKMVDKS 270
            .:.|               |.|.:|||.||...::||...   :.:........|..||:  :|.
Yeast   132 PVTT---------------DAIILATGASAKRMHLPGEETYWQQGISACAVCDGAVPIFR--NKP 179

  Fly   271 TQVVCLGSSFMAVEATANLVSRARSVTLVARQNVPFKSTLGELIGQRILKLLEENKVDLRMSSGI 335
            ..|:..|.|  |.|....|...|..|.::.|:: .|::::  ::.:||     |...::.:....
Yeast   180 LAVIGGGDS--ACEEAEFLTKYASKVYILVRKD-HFRASV--IMQRRI-----EKNPNIIVLFNT 234

  Fly   336 IRILGNSRGEVVAVKLLDNSR------IPCNLLILGTGCQCNTDFL------QRSG-ININPNGS 387
            :.:.....|:::.:..:.|::      :..|.|....|....||.:      :.:| |...|..|
Yeast   235 VALEAKGDGKLLNMLRIKNTKSNVENDLEVNGLFYAIGHSPATDIVKGQVDEEETGYIKTVPGSS 299

  Fly   388 VDVNDFLQTKVRNVYVGGDIANAYILGGFPDRVNISHYGLAQYHGRIAALNMSGHIAKLE 447
            :       |.|...:..||:.::..      |..::..|    .|.||||:...:::..|
Yeast   300 L-------TSVPGFFAAGDVQDSRY------RQAVTSAG----SGCIAALDAERYLSAQE 342

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10700	NP_609942.1	Rieske_AIFL_N	10..106	CDD:239560	10/26 (38%)
		Pyr_redox_2	135..414	CDD:285266	54/294 (18%)
		Pyr_redox	273..350	CDD:278498	14/76 (18%)
		COG3393	336..>508	CDD:225928	23/125 (18%)
		Reductase_C	464..527	CDD:291425
TRR2	NP_011974.1	TRX_reduct	28..338	CDD:273540	71/379 (19%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157345490
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.840