Protein Alignment CG10700 and PYROXD1

DIOPT Version :9

• Sequence 1: NP_609942.1
• Gene: CG10700 / 35183
• FlyBaseID: FBgn0032754
• Length: 539
• Species: Drosophila melanogaster
• Sequence 2: NP_079130.2
• Gene: PYROXD1 / 79912
• HGNCID: 26162
• Length: 500
• Species: Homo sapiens
• Alignment Length: 459
• Identity: 77/459 - (16%)
• Similarity: 153/459 - (33%)
• Gaps: 151/459 - (32%)

  Fly   134 FVVVGGGPSGAVCVETLRQEGFTGRLTLVCGEKHLPYD------RTRIMNLLNTYTKNLALREEQ 192
            |||||||.:|..|.|.|              ..|.|.:      .:.::..:..:.:...:.||
Human    13 FVVVGGGIAGVTCAEQL--------------ATHFPSEDILLVTASPVIKAVTNFKQISKILEE- 62

  Fly   193 FYKDYGIEMQLGVSAERLDTNCNTL-----------HC---TNGKTFPYDKIYIATGYSAV---- 239
                :.:|.|......:...|...:           ||   .:|....|.|:.:..|....
Human    63 ----FDVEEQSSTMLGKRFPNIKVIESGVKQLKSEEHCIVTEDGNQHVYKKLCLCAGAKPKLICE 123

  Fly   240 -TPNIPGVHLKNVKVIRNIGDARSIFKMVDKSTQVVCLGSSFMAVE------------------- 284
             .|.:.|        ||:...|:...|.:.|:.:::.:|:..:|:|
Human   124 GNPYVLG--------IRDTDSAQEFQKQLTKAKRIMIIGNGGIALELVYEIEGCEVIWAIKDKAI 180

  Fly   285 ------------ATANLVS----------RARSVTLVARQNVPFKS---TLGELIGQ-------- 316
                        .|:.|::          |.|..|...::....||   .:|..:|.
Human   181 GNTFFDAGAAEFLTSKLIAEKSEAKIAHKRTRYTTEGRKKEARSKSKADNVGSALGPDWHEGLNL 245

  Fly   317 ----------RILKLLEENKVDLRMSSGIIR------------ILGNSRGEVVAVKLLDNSRIPC 359
                      .:..:.|..|:.|:....|::            :..::....|.|:|.:.....|
Human   246 KGTKEFSHKIHLETMCEVKKIYLQDEFRILKKKSFTFPRDHKSVTADTEMWPVYVELTNEKIYGC 310

  Fly   360 NLLILGTGCQCNTD-FLQRSGININPNGSVDVNDFLQTKVRNVYVGGDI-ANAYILGGFPDRVNI 422
            :.::..||...|.: ||..:..::..:|.:.|:|.:.|.:.::|..||| ..::.|.....::.:
Human   311 DFIVSATGVTPNVEPFLHGNSFDLGEDGGLKVDDHMHTSLPDIYAAGDICTTSWQLSPVWQQMRL 375

  Fly   423 SHYGLAQYHGRIAALNMS-----------------GHIAKLEAIPFFYTVIFGRAFRSAGYGPFK 470
              :..|:..|..||..|:                 .|:.|.    |.|.|:....:.:.|.|...
Human   376 --WTQARQMGWYAAKCMAAASSGDSIDMDFSFELFAHVTKF----FNYKVVLLGKYNAQGLGSDH 434

  Fly   471 DVVI 474
            ::::
Human   435 ELML 438

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10700	NP_609942.1	Rieske_AIFL_N	10..106	CDD:239560
		Pyr_redox_2	135..414	CDD:285266	63/379 (17%)
		Pyr_redox	273..350	CDD:278498	17/150 (11%)
		COG3393	336..>508	CDD:225928	30/170 (18%)
		Reductase_C	464..527	CDD:291425	2/11 (18%)
PYROXD1	NP_079130.2	Pyr_redox_2	24..383	CDD:330998	58/387 (15%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	211..235		5/23 (22%)
		NirB	<300..>494	CDD:330997	29/145 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0446
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900