DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17572 and Masp2

DIOPT Version :9

Sequence 1:	NP_609941.2	Gene:	CG17572 / 35182	FlyBaseID:	FBgn0032753	Length:	385	Species:	Drosophila melanogaster
Sequence 2:	NP_742040.1	Gene:	Masp2 / 64459	RGDID:	620214	Length:	685	Species:	Rattus norvegicus

Alignment Length:	385	Identity:	108/385 - (28%)
Similarity:	159/385 - (41%)	Gaps:	97/385 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    51 SVAARSYYDVVQNAGQ-----TGCSVGTECTPLHD-------------CTALIYEVARSCYYGDK 97
            ||..:|:..|.|..|.     ..||: .:|.|..|             .|.....:..||   ::
  Rat   338 SVPLKSFTAVCQKDGSWDRPIPECSI-IDCGPPDDLPNGHVDYITGPEVTTYKAVIQYSC---EE 398

  Fly    98 SLYCGGSSEELPYVC-----CPSSPLEKN-----QVCGKS-------LVQGHFYKGLGSYPF-VA 144
            :.|...|:.:  |||     ..||..||:     .|||.|       ::.|...|. |.:|: |.
  Rat   399 TFYTMSSNGK--YVCEADGFWTSSKGEKSLPVCKPVCGLSTHTSGGRIIGGQPAKP-GDFPWQVL 460

  Fly   145 RIGFKHVNTGAFAYPCAGAVIARRVILTAAHCALAKADGHRLSSVRVG------EYDTSSDPDCA 203
            .:|    .|.|     |||:|....:|||||....|.:......:|:|      .:.|.:.|:.
  Rat   461 LLG----ETTA-----AGALIHDDWVLTAAHAVYGKTEAMSSLDIRMGILKRLSPHYTQAWPEA- 515

  Fly   204 NTGFCAPRSVNHAISHVIVHPDYKQGQ-YHHDIALLVLKTPLNYSVATQPICL-QKTRANLV--- 263
                            |.:|..|..|. :.:||||:.||..:..:....|||| :|..|:|:
  Rat   516 ----------------VFIHEGYTHGAGFDNDIALIKLKNKVTINRNIMPICLPRKEAASLMKTD 564

  Fly   264 -VGKRATIAGWGKMSTSSVRQPEMSHLDVPLTSWDLCLRNYGS---TGALESPNSIEGQWMCAG- 323
             ||   |:|||| ::........:..:|:|:.....|...|..   .||..:.|     .:|||
  Rat   565 FVG---TVAGWG-LTQKGFLARNLMFVDIPIVDHQKCATAYTKQPYPGAKVTVN-----MLCAGL 620

  Fly   324 -GEGKDVCQG-FGGAPLFI-QENGIFSQIGIMSFGSDNCGGLRIPSVYTSVAHFSEWIHD 380
             ..|||.|:| .|||.:|: .|...:...||:|:||.||||.....|||.|.::..||.:
  Rat   621 DAGGKDSCRGDSGGALVFLDNETQRWFVGGIVSWGSINCGGSEQYGVYTKVTNYIPWIEN 680

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17572	NP_609941.2	Tryp_SPc	138..381	CDD:238113	79/263 (30%)
CG17572	NP_609941.2	Tryp_SPc	138..378	CDD:214473	77/259 (30%)
Masp2	NP_742040.1	CUB	19..136	CDD:238001
		FXa_inhibition	152..180	CDD:291342
		CUB	184..295	CDD:238001
		Sushi	300..361	CDD:278512	6/22 (27%)
		Sushi	366..429	CDD:278512	15/67 (22%)
		Tryp_SPc	443..678	CDD:214473	79/270 (29%)
		Tryp_SPc	444..681	CDD:238113	81/273 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910