DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG17572 and C1s

DIOPT Version :9

Sequence 1:	NP_609941.2	Gene:	CG17572 / 35182	FlyBaseID:	FBgn0032753	Length:	385	Species:	Drosophila melanogaster
Sequence 2:	NP_620255.2	Gene:	C1s / 192262	RGDID:	619983	Length:	694	Species:	Rattus norvegicus

Alignment Length:	409	Identity:	97/409 - (23%)
Similarity:	160/409 - (39%)	Gaps:	117/409 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly    46 ETTGHSVAARSYYDVVQNAGQTGCSVGTECTPLHDC--------------------TALIYEVAR 90
            |....:|.:.|:|...|:.||...| ..||.|: ||                    :.:.|....
  Rat   332 EVVEGNVGSTSFYSTCQSNGQWSNS-RLECQPV-DCGVPEPIENGKVEDPEDTVFGSVIHYTCEE 394

  Fly    91 SCYYGDK----SLYCGGSSE--------ELPYVCCPSSPLEKNQVCG--------KSLVQGHFYK 135
            ..||.::    ..:|..:..        ||| .|.|        |||        :..:.|.:..
  Rat   395 PYYYMEQEEGGEYHCAANGSWVNDQLGVELP-KCIP--------VCGVPTEPFKVQQRIFGGYST 450

  Fly   136 GLGSYPFVARIGFKHVNTGAFAYPCAGAVIARRVILTAAHCALAKAD-----GHRLSSVRVGEYD 195
            .:.|:|:  ::.|:....|       ||:|....:|||||.....:|     |..|..:.
  Rat   451 KIQSFPW--QVYFESPRGG-------GALIDEYWVLTAAHVVEGNSDPVMYVGSTLLKIE----- 501

  Fly   196 TSSDPDCANTGFCAPRSVNHAIS-HVIVHPDYKQ-------GQYHHDIALLVLKTPLNYSVATQP 252
                         ..|:....|: .||:||.:||       ..:.:||||:.||.|:.......|
  Rat   502 -------------RLRNAQRLITERVIIHPSWKQEDDLNTRTNFDNDIALVQLKDPVKMGPTVAP 553

  Fly   253 ICLQKTRA--NLVVGKRATIAGWGKMSTSSVRQPEMSHLDVPLTSWDLCLRNYGSTGALESPNSI 315
            |||.:|.:  |...|....|:|||: :.:.....::....:|:||.:.|     ....:|:|.:.
  Rat   554 ICLPETSSDYNPSEGDLGLISGWGR-TENRTNVIQLRGAKLPITSLEKC-----QQVKVENPKAR 612

  Fly   316 EGQW------MCAGGEGKDVCQG-FGGA---PLFIQENGIFSQIGIMSFGSDNCGGLRIPSVYTS 370
            ...:      :|||.:|.|.|:| .|||   |:...::..|...|::|:|. .||..   .:||.
  Rat   613 SNDYVFTDNMICAGEKGVDSCEGDSGGAFALPVPNVKDPKFYVAGLVSWGK-KCGTY---GIYTK 673

  Fly   371 VAHFSEWI----HDNTPPE 385
            |.::.:||    .:|:.|:
  Rat   674 VKNYVDWILKTMQENSGPK 692

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17572	NP_609941.2	Tryp_SPc	138..381	CDD:238113	69/271 (25%)
CG17572	NP_609941.2	Tryp_SPc	138..378	CDD:214473	67/264 (25%)
C1s	NP_620255.2	CUB	24..135	CDD:238001
		FXa_inhibition	149..177	CDD:405372
		CUB	181..293	CDD:395345
		CCP	300..361	CDD:153056	9/29 (31%)
		CCP	365..428	CDD:153056	8/63 (13%)
		Tryp_SPc	443..681	CDD:214473	68/274 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000