DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17572 and svh-1

DIOPT Version :9

Sequence 1:	NP_609941.2	Gene:	CG17572 / 35182	FlyBaseID:	FBgn0032753	Length:	385	Species:	Drosophila melanogaster
Sequence 2:	NP_501379.2	Gene:	svh-1 / 182375	WormBaseID:	WBGene00006620	Length:	951	Species:	Caenorhabditis elegans

Alignment Length:	318	Identity:	79/318 - (24%)
Similarity:	138/318 - (43%)	Gaps:	48/318 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    69 CSV--GTECTPLHDCTALIYEVARSCYYGDKSLYCGGSSEELPYVCCPSSPLEKNQVCGKSLVQG 131
            ||:  .:.|| .|...:.|.:...|     .:..||     |.||...:....|:::   :.|.|
Worm   665 CSIRRSSSCT-RHARISCISQNGMS-----SASQCG-----LRYVEVNARDAAKSRI---ARVVG 715

  Fly   132 HFYKGLGSYPFVARIGFKHVNTGAFAYPCAGAVIARRVILTAAHCALAKADGHRLSS--VRVGEY 194
            .|....|::|:.|.:.    |....|:.|..:::.:..::|||||.   .:..|:||  |.||::
Worm   716 GFETVPGAFPWTAALR----NKATKAHHCGASILDKTHLITAAHCF---EEDERVSSYEVVVGDW 773

  Fly   195 DTSSDPDCANTGFCAPRSVNHAISHVIVHPDYKQGQYHHDIALLVLKTP-LNYSVATQPICLQKT 258
            |.:.........:         :..:..:|.||. .:.||||:|.:..| :.::...|||||...
Worm   774 DNNQTDGNEQIFY---------LQRIHFYPLYKD-IFSHDIAILEIPYPGIEFNEYAQPICLPSK 828

  Fly   259 RANLVVGKRATIAGWGKMSTSSVRQPEMSHLDVPLTSWDLCLRNYGSTGALESPNSIEGQWMCAG 323
            ......|::..::|||.|......:.:.:.:.:        :..:....:.:..:|:.....|||
Worm   829 DFVYTPGRQCVVSGWGSMGLRYAERLQAALIPI--------INRFDCVNSSQIYSSMSRSAFCAG 885

  Fly   324 --GEGKDVCQGFGGAPLFI-QENGIFSQIGIMSFGSDNCGGLRIPSVYTSVAHFSEWI 378
              ..|.|.|||..|.|... :|:|.|...|::|:| |.|...:.|.:||.||.:..||
Worm   886 YLEGGIDSCQGDSGGPFACRREDGAFVLAGVISWG-DGCAQKKQPGIYTMVAPYLSWI 942

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17572	NP_609941.2	Tryp_SPc	138..381	CDD:238113	63/247 (26%)
CG17572	NP_609941.2	Tryp_SPc	138..378	CDD:214473	61/245 (25%)
svh-1	NP_501379.2	KR	227..306	CDD:214527
		LDLa	320..355	CDD:238060
		PAN_AP_HGF	373..434	CDD:238532
		LDLa	558..590	CDD:197566
		SRCR_2	599..681	CDD:382996	5/16 (31%)
		Tryp_SPc	713..945	CDD:238113	66/256 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910