DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10702 and Ack

DIOPT Version :9

Sequence 1:	NP_001188841.1	Gene:	CG10702 / 35181	FlyBaseID:	FBgn0032752	Length:	946	Species:	Drosophila melanogaster
Sequence 2:	NP_647859.1	Gene:	Ack / 38489	FlyBaseID:	FBgn0028484	Length:	1073	Species:	Drosophila melanogaster

Alignment Length:	287	Identity:	55/287 - (19%)
Similarity:	92/287 - (32%)	Gaps:	88/287 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly   371 LRSLQFLRNLERVHGDPLENR--HYSFILYDNKELSELWTPS-RQLEFMEGGMFMHRNNKLCNRR 432
            ||.:|..:.|:|:..|....|  |:.::|.|:.|...|..|: |:|      |...|..|....|
  Fly    22 LREVQLEQFLDRIRDDLQVTRLAHFDYVLPDDLERCGLGKPAIRRL------MEAVRKKKAHQWR 80

  Fly   433 MREFQNAV----------THDRALDSLQTNDQEVQCSPLKLQLYVQKRTHRSVKL---------- 477
            .......:          ....|.:|.|.|..::.|      |..:|.....:||
  Fly    81 KNILSKLIGGGKQPSSKKQSSAARESSQGNGTQLTC------LIHEKDITMGLKLGDGSFGVVRR 139

  Fly   478 -SWLKSQTSQKIELIHRPLLPGKLYHEESELDAPICTRINWKRRLLFPDDLIENGTHYLFDLDDL 541
             .|..|...:.|                     |:..::      |..|:|.:.|.     :||.
  Fly   140 GEWSASPAGKVI---------------------PVAVKV------LKSDNLTQPGI-----IDDF 172

  Fly   542 QPDTRYVVLLRTFGNDEAHEAYEARSELTYVQTELDIPKPPLLELVKKTDSSLTVQMASHDHVSF 606
                        |...:|..|.:..:.:......|..|...:.||.:: .|.|........|.|
  Fly   173 ------------FREVQAMHALDHANLVRLYGVVLSQPMMMITELAER-GSLLDTLRKQCRHTS- 223

  Fly   607 LLTVF-----ELSDDQDYIEQRNYCHQ 628
             ||:.     ::.....|:||:.:.|:
  Fly   224 -LTIIWNWSVQIVTGMAYLEQKRFLHR 249

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10702	NP_001188841.1	Recep_L_domain	47..159	CDD:279382
		Furin-like	171..297	CDD:279142
		FU	210..258	CDD:238021
		Recep_L_domain	328..441	CDD:279382	19/82 (23%)
Ack	NP_647859.1	SAM_TNK-like	14..75	CDD:188938	17/58 (29%)
		PTKc_Ack_like	128..385	CDD:270636	29/169 (17%)
		UBA_TNK1	1031..1070	CDD:270513
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45468377
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.930