Protein Alignment CG10702 and Fak

DIOPT Version :10

• Sequence 1: NP_724157.1
• Gene: CG10702 / 35181
• FlyBaseID: FBgn0032752
• Length: 946
• Species: Drosophila melanogaster
• Sequence 2: NP_001137718.1
• Gene: Fak / 37233
• FlyBaseID: FBgn0020440
• Length: 1500
• Species: Drosophila melanogaster
• Alignment Length: 665
• Identity: 121/665 - (18%)
• Similarity: 203/665 - (30%)
• Gaps: 228/665 - (34%)

  Fly   134 IQRGQVYIGSCPKLCSIGRVNWDLLTLTRGENNIIMVNKNCS---------TPVCSGCSSSHCWS 189
            |:|....:|:..:..||.|....:|.:...|  :|.:.::.|         ||   |||:..|.:
  Fly    48 IRRTVEDLGTDGRTPSIQRYACRMLNMITKE--VIWLARSTSMQKVLSHILTP---GCSNVDCPN 107

  Fly   190 N---------------------------HYCQRSINENVANPK----------------ANINAC 211
            |                           .|...:|.|.....|                ||:.|.
  Fly   108 NQSELDEVLLEHGRRITDNRVWRVELRVRYVPNNIQELFEEDKATCFYYFNQVKEDFIQANVTAI 172

  Fly   212 HEE------CLG---GCKNNSSSPADCSV----------CRGLSDDGVCVKSCPKD--KYVMENY 255
            ..|      |||   ..||.:....|...          .:......|...|.||:  |.:...|
  Fly   173 DTEVAVQLCCLGIRHYFKNITVKAPDKKQHIDYIEKEIGFKSFLPQSVIATSKPKNLKKLIQVGY 237

  Fly   256 QRCY--------TKAECVLKHGYVISGSQCVAFCPSGYKTNNRSECVLCSPDEACISFCT-PEWP 311
            ::.|        |:...:||:.|:.:..|......|.:..:.    :|.......||:.| |:..
  Fly   238 KKVYNYNDIEYLTRFFDLLKNIYLTNFEQFSVTLSSAWNISG----ILHVGPHIGISYQTHPQAS 298

  Fly   312 GKAFTVYNLADAENLRGCQIFNGSLVITIRNKVNETQLYQSFTSMREVRGHVKVYRSSQLRSLQF 376
            .|  .|....|..:::.|.:....|..:..| ..|.:|.....:.::::..:|:..|:.:..|..
  Fly   299 LK--NVAQFKDVVSIKTCTLPKEKLSKSGEN-TTEPELQNFNCNCQKIKTQIKISASNNVEDLVI 360

  Fly   377 ----LRNLERVHGDPLENRHYSFILYDNKELSELWTPSRQLEFMEGGMFMHRNNKLCNRRMREFQ 437
                :...|.: .|.::.  |..:|            |:.|||    ...||.....|   .:..
  Fly   361 TCNGINTAESI-ADLIDG--YCRLL------------SKDLEF----TIWHRETNASN---EDSA 403

  Fly   438 NAVTHDRALDSLQTNDQEVQCSPLKLQLYVQKRTHRSVKLSWLKSQTSQKIELIHRPLLPGK--- 499
            .|:.:|..|.|                               .||.:||     .:|:|...
  Fly   404 KALPNDATLGS-------------------------------NKSTSSQ-----GKPMLTDDYAE 432

  Fly   500 --LYHEESELDAPICTRINWKRRLLFPD-------------------------DLIENGTHYLFD 537
              |...|.:...|........|.|:.|.                         :|..||.:...|
  Fly   433 IGLLEGEGDYSTPTVRNYELDRALITPSAKIGVGQFGDVYVGTYTLPKLGKGKNLAGNGKNSNSD 497

  Fly   538 L--DDLQPDTRYVVLLRTFGNDEAHEAYEARSELTYVQTELDIPK----------PPL---LELV 587
            .  .|.:||...|.:.....||:..:.....:| .|:..:.|.|.          .|:   :||.
  Fly   498 QRNADSRPDVIQVAIKTCKANDDPEKTENFLAE-AYIMQKFDHPHIIRLIGICSVMPIWIVMELA 561

  Fly   588 K--------KTDSSLTVQMASHDHVSFLLTVFELSDDQDYIEQRNYCHQ-----------PSYV- 632
            |        ||:|...      .|.:.|...::||....|:|.:.:.|:           |:.|
  Fly   562 KLGELRAYLKTNSERL------SHGTLLKYCYQLSTALSYLESKKFVHRDIAARNVLVSSPTCVK 620

  Fly   633 WQDMDGPRWMAYEDY 647
            ..|....||::.:.|
  Fly   621 LADFGLSRWVSDQSY 635

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10702	NP_724157.1	Recep_L_domain	47..159	CDD:460032	6/24 (25%)
		Furin-like	171..297	CDD:395614	36/206 (17%)
		Recep_L_domain	328..441	CDD:460032	20/116 (17%)
Fak	NP_001137718.1	B41	24..267	CDD:214604	42/223 (19%)
		FERM_B-lobe	152..257	CDD:271216	18/104 (17%)
		FERM_C_FAK1	263..394	CDD:270011	27/156 (17%)
		PTKc_FAK	450..744	CDD:133187	37/193 (19%)
		Focal_AT	1250..1376	CDD:460992