Protein Alignment CG10702 and Btk29A

DIOPT Version :9

• Sequence 1: NP_001188841.1
• Gene: CG10702 / 35181
• FlyBaseID: FBgn0032752
• Length: 946
• Species: Drosophila melanogaster
• Sequence 2: NP_001097121.1
• Gene: Btk29A / 34132
• FlyBaseID: FBgn0003502
• Length: 786
• Species: Drosophila melanogaster
• Alignment Length: 570
• Identity: 99/570 - (17%)
• Similarity: 186/570 - (32%)
• Gaps: 187/570 - (32%)

  Fly   181 GCSSSHCWSNHYCQRSINENVAN---PKANI------NACHEECLGGCKNNSSSPADCSVCRGL- 235
            ||.::..|      |..|.|.:|   |..|.      |:.........::|||......|..||
  Fly   216 GCRAAAHW------REANNNPSNGSSPAQNSTRSISPNSSTTNSQFSLQHNSSGSLGGGVGGGLG 274

  Fly   236 -----------SDDGVCVKSCPKDKYVMENYQRCYTKAECVLKHGYVISGSQCVAFCPSGYKT-- 287
                       ...|.|..:..:.:..:..:::..|     |.:|   :|:...|..|.|..|
  Fly   275 GGGSLGLGGGGGGGGSCTPTSLQPQSSLTTFKQSPT-----LLNG---NGTLLDANMPGGIPTPG 331

  Fly   288 --NNRSECVLCSPDEACISFCTPEWPGKAFTVYNLADAENLRGCQIFNGSLVITIRNKVNETQLY 350
              |::::     .:...:......:|.||....:|:..:|..             ...::::|
  Fly   332 TPNSKAK-----DNSHFVKLVVALYPFKAIEGGDLSLEKNAE-------------YEVIDDSQ-- 376

  Fly   351 QSFTSMREVRGHVKVYRSSQLRSLQFLRNLERVH---GDPLENRHYSFILYDNKELSELWTPSRQ 412
            :.:..:::..|:|....|:.::. :.|..|||..   ||....|..|.:...:||
  Fly   377 EHWWKVKDALGNVGYIPSNYVKP-KALLGLERYEWYVGDMSRQRAESLLKQGDKE---------- 430

  Fly   413 LEFMEGGMFMHRNNK-----LCNRRMREFQNAVTHDRALDSLQTNDQEVQCSPLKLQLYVQKR-- 470
                  |.|:.|.:.     ..:...:..|:.|.|...       .|..:|     :.|:.::
  Fly   431 ------GCFVVRKSSTKGLYTLSLHTKVPQSHVKHYHI-------KQNARC-----EYYLSEKHC 477

  Fly   471 -----------THRSVKLSW-LKSQTSQKIELIHRPLLP-GKLYHEESEL--------------D 508
                       .|.|..|:. |||....      ||:.| ..|.|::.|:              .
  Fly   478 CETIPDLINYHRHNSGGLACRLKSSPCD------RPVPPTAGLSHDKWEIHPMELMLMEELGSGQ 536

  Fly   509 APICTRINWKRRLLFPDDLIENGTHYLFDLDDLQPDTRYVV------LLRTFGNDEAHEAYEARS 567
            ..:..|..|:..:.....:::.||   ...||...:.:.:.      |::.:|....|..
  Fly   537 FGVVRRGKWRGSIDTAVKMMKEGT---MSEDDFIEEAKVMTKLQHPNLVQLYGVCSKHRP----- 593

  Fly   568 ELTYVQTELDIPKPPLLELVKKTDSSLTVQMASHDHVSFLLTV-FELSDDQDYIEQRNYCHQPSY 631
              .|:.||. :....||..:::.:.:|...|      ..||.: .::|....|:|:.||.|:
  Fly   594 --IYIVTEY-MKHGSLLNYLRRHEKTLIGNM------GLLLDMCIQVSKGMTYLERHNYIHR--- 646

  Fly   632 VWQDMDGPRWMAYEDYDDCCAQ----------KAEQFEDSRFIADMREQY 671
                             |..|:          |...|..:|::.|  :||
  Fly   647 -----------------DLAARNCLVGSENVVKVADFGLARYVLD--DQY 677

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10702	NP_001188841.1	Recep_L_domain	47..159	CDD:279382
		Furin-like	171..297	CDD:279142	27/140 (19%)
		FU	210..258	CDD:238021	8/59 (14%)
		Recep_L_domain	328..441	CDD:279382	18/120 (15%)
Btk29A	NP_001097121.1	PH_Btk	44..222	CDD:269944	2/5 (40%)
		SH3_Tec_like	346..399	CDD:212702	9/67 (13%)
		SH2_Tec_family	403..505	CDD:198188	24/129 (19%)
		PTKc_Tec_like	521..778	CDD:173637	32/196 (16%)
		Pkinase_Tyr	526..777	CDD:285015	32/191 (17%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45468347
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.930