DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10702 and rol-3

DIOPT Version :9

Sequence 1:	NP_001188841.1	Gene:	CG10702 / 35181	FlyBaseID:	FBgn0032752	Length:	946	Species:	Drosophila melanogaster
Sequence 2:	NP_001256097.1	Gene:	rol-3 / 179204	WormBaseID:	WBGene00004395	Length:	2481	Species:	Caenorhabditis elegans

Alignment Length:	248	Identity:	56/248 - (22%)
Similarity:	97/248 - (39%)	Gaps:	54/248 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly   396 ILYDN-------KELSELWTPSRQ---LEFMEGG---MFMHRNNKLCNRRMREFQNAVTHDRALD 447
            ||.:|       |||....||.::   ||:||||   .|:.::..      .|:|::....|.|.
Worm  2020 ILLNNLDHPNIVKELGVCITPGQELILLEYMEGGNLLKFLQKSTP------NEYQSSELSPRDLL 2078

  Fly   448 SLQTNDQEVQCSPLKLQLYVQKRTHRSVKLSWLKSQTS-----QKIEL-IHRPLLPGKLYHEESE 506
            |:..:       ..:...|:::..|....||..|...:     .|:|: :.:.|..|::...:.|
Worm  2079 SISVD-------IARGMNYLERLPHVHKNLSARKCLLAGRPGVTKLEMGMSKELSNGQVNRSDLE 2136

  Fly   507 LDAPICTRINWKRRLLFPDDLIENGTHYLFDLDDLQPDTRYVVLLR---TFGNDEAHEAYEARSE 568
             :..|   :.|    :.|:.|.:      |..........|.|||.   :|| :..:...:.|..
Worm  2137 -NMEI---VRW----MAPEVLKD------FQFSSKSDVWAYGVLLYEVFSFG-EVPYGDKDNRRI 2186

  Fly   569 LTYVQTELDIPKP---PLLELVKKTDSSLTVQMASHDHVSFLLTVFE-LSDDQ 617
            :|.|:....:|.|   |...:.|.....||.......:.:.:|.:|| ..|||
Worm  2187 MTDVRNGSVLPIPSYCPSKRIYKVIKQCLTSDSTKRANFATILKIFETFRDDQ 2239

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10702	NP_001188841.1	Recep_L_domain	47..159	CDD:279382
		Furin-like	171..297	CDD:279142
		FU	210..258	CDD:238021
		Recep_L_domain	328..441	CDD:279382	17/57 (30%)
rol-3	NP_001256097.1	FN3	1542..1636	CDD:238020
		fn3	1664..1749	CDD:278470
		STYKc	1966..2232	CDD:214568	51/239 (21%)
		PTKc	1970..2233	CDD:270623	51/240 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160156323
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	3	2.800