DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10495 and dus4l

DIOPT Version :9

Sequence 1:	NP_609939.1	Gene:	CG10495 / 35179	FlyBaseID:	FBgn0032750	Length:	396	Species:	Drosophila melanogaster
Sequence 2:	NP_001003490.2	Gene:	dus4l / 445096	ZFINID:	ZDB-GENE-040801-233	Length:	307	Species:	Danio rerio

Alignment Length:	299	Identity:	135/299 - (45%)
Similarity:	195/299 - (65%)	Gaps:	12/299 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly    24 VRVSAPMVRYSKLEFRRLVRLNGVQLAFTPMMISDSINNSEKARQNEFSTGADDQPLIAQFAAKD 88
            |||.|||||||||.||.|||.....:.||||:|:.....|.|||.:||:|..:|:|||.||||||
Zfish    17 VRVCAPMVRYSKLAFRTLVRKYDCDVCFTPMIIAADFMRSAKARDSEFTTNKNDRPLIVQFAAKD 81

  Fly    89 PTEFVTSAQLIYPYVDGIDLNCGCPQSWAMAKGYGCGMLRQPELVHQVVQEVRRTLPG-DFSVSV 152
            ......:|.::.|:.||:||||||||.|||::|||..::.:||||..:|:.||..:.. :::||:
Zfish    82 AQTLADAACVVSPFSDGVDLNCGCPQRWAMSEGYGACLINKPELVKDMVRHVRNQIDNPNYAVSI 146

  Fly   153 KMRLLGGEESLQRTIDLARQLESAGVTFLTLHGRTPAQKHSKDTLDIPAMSQVRQSLQIPLIVNG 217
            |:|:   .:.:::|:||.:::|:|||:::|:||||..::|.....|  .:..::.||.||:|.||
Zfish   147 KIRI---HKDVRQTVDLCQKVEAAGVSYITVHGRTAIERHQPVHYD--TIKTIKDSLSIPVIANG 206

  Fly   218 NVESYRDACDMHEQTGAAGVMAARGLLANPALFNSNYPDGKTTPLSCVQQWLDIASAAGDNLLFQ 282
            :::|.:|...:.|.||..|||:|||||:|||:| |.:.:   |||.||..|:|||:..|..  |.
Zfish   207 DIKSMQDVEAVCELTGVDGVMSARGLLSNPAMF-SGFEE---TPLQCVWDWVDIAAEHGTP--FT 265

  Fly   283 CFHHHLTFMYSAQMKRDLRVQFNSLGSKEQVVDFLKEHY 321
            ||||||..|......:..|..||:|.|...|:|||...|
Zfish   266 CFHHHLIHMLERITSQPERRVFNNLSSTSAVIDFLHNTY 304

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10495	NP_609939.1	DUS_like_FMN	26..251	CDD:239200	103/225 (46%)
CG10495	NP_609939.1	Dus	28..321	CDD:279540	131/293 (45%)
dus4l	NP_001003490.2	DusA	15..300	CDD:223120	132/293 (45%)
dus4l	NP_001003490.2	DUS_like_FMN	19..246	CDD:239200	105/235 (45%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170578434
Domainoid	1	1.000	238	1.000	Domainoid score	I2242
eggNOG	1	0.900	-	-		E1_COG0042
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H6535
Inparanoid	1	1.050	257	1.000	Inparanoid score	I3136
OMA	1	1.010	-	-		QHG54379
OrthoDB	1	1.010	-	-		D1345916at2759
OrthoFinder	1	1.000	-	-		FOG0004835
OrthoInspector	1	1.000	-	-		oto39805
orthoMCL	1	0.900	-	-		OOG6_104072
Panther	1	1.100	-	-	LDO	PTHR11082
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R357
SonicParanoid	1	1.000	-	-		X4511
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	17	16.800