DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10495 and Dus3l

DIOPT Version :9

Sequence 1:	NP_609939.1	Gene:	CG10495 / 35179	FlyBaseID:	FBgn0032750	Length:	396	Species:	Drosophila melanogaster
Sequence 2:	NP_001030095.1	Gene:	Dus3l / 301122	RGDID:	1563228	Length:	640	Species:	Rattus norvegicus

Alignment Length:	275	Identity:	80/275 - (29%)
Similarity:	128/275 - (46%)	Gaps:	40/275 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    28 APMVRYSKLEFRRLVRLNGVQLAFTPMMISDSINNSEKARQNEFSTGADDQPLIAQFAAKD---- 88
            ||:.....|.|||:.:..|..:....|.:..::      .|.:.|..|    |:.:...:|
  Rat   300 APLTTCGNLPFRRICKRFGADVTCGEMAMCTNL------LQGQMSEWA----LLKRHPCEDIFGV 354

  Fly    89 ------PTEFVTSAQLIYPY--VDGIDLNCGCPQSWAMAKGYGCGMLRQPELVHQVVQEVRRTLP 145
                  |......|:|:...  ||.:|:|.|||......||.||.::.:.....|:|:.:...|
  Rat   355 QLEGAFPDTMTKCAELLNRTIDVDFVDINVGCPIDLVYKKGGGCALMNRSAKFQQIVRGMNEVL- 418

  Fly   146 GDFSVSVKMRLLGGEESLQRTIDLARQLESAGVTFLTLHGRTPAQKHSKDTLDIPAMSQ-VRQSL 209
             |..::|||| .|.:|.:.....|..:|.:.||..:|||||:..|:::: ..|.|.:.| .:.:.
  Rat   419 -DVPLTVKMR-TGVQERVSLAHRLLPELRNWGVALVTLHGRSREQRYTR-LADWPYIEQCAKVAS 480

  Fly   210 QIPLIVNGNVESYRDA-CDMHEQTGAAGVMAARGLLANPALFNSNYPDGKTTPLSCVQQWLDIAS 273
            .:||..||::.|:.|| |.|  |||.||:|.|||.|..|.||         |.:...:.| ||:|
  Rat   481 PMPLFGNGDILSFEDANCAM--QTGVAGIMVARGALLKPWLF---------TEIKEQRHW-DISS 533

  Fly   274 AAGDNLLFQCFHHHL 288
            :...::|....|:.|
  Rat   534 SERLDILRDFTHYGL 548

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10495	NP_609939.1	DUS_like_FMN	26..251	CDD:239200	71/236 (30%)
CG10495	NP_609939.1	Dus	28..321	CDD:279540	80/275 (29%)
Dus3l	NP_001030095.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..22
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	47..106
		DusA	287..566	CDD:223120	80/275 (29%)
		DUS_like_FMN	296..528	CDD:239200	73/252 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0042
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810