DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Phlpp and AT1G72840

DIOPT Version :9

Sequence 1:	NP_001260558.1	Gene:	Phlpp / 35178	FlyBaseID:	FBgn0032749	Length:	954	Species:	Drosophila melanogaster
Sequence 2:	NP_001185386.1	Gene:	AT1G72840 / 843615	AraportID:	AT1G72840	Length:	1183	Species:	Arabidopsis thaliana

Alignment Length:	577	Identity:	120/577 - (20%)
Similarity:	210/577 - (36%)	Gaps:	157/577 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly    58 LGGSILIGNYNYLTQLEVCENEMEVL--DLSSLAQLETLKCSRNKLMELIINGTNLQTLVADHNY 120
            |||:  :.|...::...|....:::|  |...|..|..: ...:.::||.:..:.|.:|......
plant   563 LGGN--VSNLQLISDDYVLSRNLKLLHWDAYPLTILPPI-FRPHTIIELSLRYSKLNSLWDGTKL 624

  Fly   121 LHNISTTNTHPVPLKLQRIDIS-HNNFSELPNW----------VGACASLTAINASHNRLNNVAV 174
            |.|            |:.:|:: ..|..|||..          :.:|.||..|..|.|||
plant   625 LPN------------LRILDVTGSRNLRELPELSTAVNLEELILESCTSLVQIPESINRL----- 672

  Fly   175 LLRNYRITELVSLD--LAYNDLKQLDQFPEGFSSIRSLQLQSNELPSLPDNFFAVTHARLETLNV 237
            .||...:.....|:  :..|||::......|...|         :.:||.:  ..|.:.|..|.:
plant   673 YLRKLNMMYCDGLEGVILVNDLQEASLSRWGLKRI---------ILNLPHS--GATLSSLTDLAI 726

  Fly   238 SCN---KLSTLPRYEQNNHAALVNLSLAGNHLNDSIFEPLHNAAKLRVLHLAYN----------- 288
            ...   |||              .||..|:||:   |..:...|...|.||..:
plant   727 QGKIFIKLS--------------GLSGTGDHLS---FSSVQKTAHQSVTHLLNSGFFGLKSLDIK 774

  Fly   289 ----RIGVLPAACV--RNWPELEILVLSGNMLQQLPEEVATLGQLRVLRCCNNLLLCTP-QLAKL 346
                |:..:..:|:  .::|.|..|.|....::.:||::..|..|..|....|..:..| .:.:|
plant   775 RFSYRLDPVNFSCLSFADFPCLTELKLINLNIEDIPEDICQLQLLETLDLGGNDFVYLPTSMGQL 839

  Fly   347 AMLKVLDLSH----------NHLDRV---------NLLALVPSRNLKYLD-----------LSG- 380
            ||||.|.||:          :.::|:         :|:.::.:.....||           |.|
plant   840 AMLKYLSLSNCRRLKALPQLSQVERLVLSGCVKLGSLMGILGAGRYNLLDFCVEKCKSLGSLMGI 904

  Fly   381 ------------NLQLQVDEQQFKVCQSQSQRHW---SLVDVSGNNRAALPTTKIRQVSAQR--- 427
                        .|:|.::..:..|..|:...|:   :.:|:|......:||: ||::|..|
plant   905 LSVEKSAPGRNELLELSLENCKSLVSLSEELSHFTKLTYLDLSSLEFRRIPTS-IRELSFMRTLY 968

  Fly   428 --NQNK----TSGPWTMGFAETPGSGDCRKLSVYQLRAANYGGSDEALYGMFEALEGRGRAAQE- 485
              |.||    |..|.::.:....|   |.     .|...|:..:..     |..|:.....:.|
plant   969 LNNCNKIFSLTDLPESLKYLYAHG---CE-----SLEHVNFSSNHS-----FNHLDFSHCISLEC 1020

  Fly   486 MSHLVPDLMKQEQMVKDSAVR--DYMKFTLLAAQQQCGSVRSAALFHLTRTRAPSKV 540
            :|.||.|.|.:|.. :::..|  ...|:::.:......|.|......|.:.:|..|:
plant  1021 ISDLVRDFMNEEYS-QEAPFRLVCITKYSIASTNNMRTSWREPMRIKLPKIKAAPKL 1076

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Phlpp	NP_001260558.1	leucine-rich repeat	91..110	CDD:275380	3/18 (17%)
		LRR_8	109..169	CDD:290566	16/70 (23%)
		leucine-rich repeat	111..135	CDD:275380	4/23 (17%)
		leucine-rich repeat	136..158	CDD:275380	7/32 (22%)
		leucine-rich repeat	159..183	CDD:275380	8/23 (35%)
		leucine-rich repeat	184..209	CDD:275380	6/26 (23%)
		LRR_8	205..266	CDD:290566	12/63 (19%)
		leucine-rich repeat	210..230	CDD:275380	3/19 (16%)
		leucine-rich repeat	232..255	CDD:275380	5/25 (20%)
		LRR_RI	<256..410	CDD:238064	44/217 (20%)
		leucine-rich repeat	256..276	CDD:275380	6/19 (32%)
		LRR_8	279..359	CDD:290566	24/107 (22%)
		leucine-rich repeat	280..303	CDD:275380	5/39 (13%)
		leucine-rich repeat	304..348	CDD:275380	11/44 (25%)
		leucine-rich repeat	349..372	CDD:275380	7/41 (17%)
		PP2Cc	461..655	CDD:294085	17/83 (20%)
AT1G72840	NP_001185386.1	PLN03210	15..>947	CDD:215633	88/431 (20%)
		TIR	15..179	CDD:279864
		leucine-rich repeat	607..627	CDD:275380	5/19 (26%)
		leucine-rich repeat	628..650	CDD:275380	6/21 (29%)
		leucine-rich repeat	651..693	CDD:275380	11/46 (24%)
		leucine-rich repeat	694..720	CDD:275380	6/36 (17%)
		leucine-rich repeat	737..770	CDD:275380	10/35 (29%)
		leucine-rich repeat	796..818	CDD:275380	6/21 (29%)
		leucine-rich repeat	819..841	CDD:275380	5/21 (24%)
		leucine-rich repeat	842..857	CDD:275380	5/14 (36%)
		leucine-rich repeat	873..897	CDD:275380	3/23 (13%)
		leucine-rich repeat	917..940	CDD:275380	5/22 (23%)
		leucine-rich repeat	941..963	CDD:275380	6/22 (27%)
		leucine-rich repeat	964..988	CDD:275380	6/23 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X32
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000