DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Phlpp and AT1G63740

DIOPT Version :9

Sequence 1:	NP_001260558.1	Gene:	Phlpp / 35178	FlyBaseID:	FBgn0032749	Length:	954	Species:	Drosophila melanogaster
Sequence 2:	NP_001322890.1	Gene:	AT1G63740 / 842678	AraportID:	AT1G63740	Length:	1063	Species:	Arabidopsis thaliana

Alignment Length:	309	Identity:	70/309 - (22%)
Similarity:	114/309 - (36%)	Gaps:	101/309 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly    48 PQKL-SLKGSQLGGSILIGNY--NYLTQLEVCENEMEVL-----DLSSLAQLETLKCSRNKLMEL 104
            |.:| ||......|..|...:  .||.:|.:..|::|.|     .|::|.:||.  |...:|.||
plant   612 PHRLRSLHWEVYPGKSLPSTFRPEYLVELNLQNNKLEKLWEGTQPLTNLNKLEL--CGSLRLKEL 674

  Fly   105 --IINGTNLQTLVADHNYLHNISTTNTHPVPLKLQRIDISHNNFSELPNWVGACASLTAINASHN 167
              :.:.||                         |:|:|::            .|.||..|.:|..
plant   675 PDLSSATN-------------------------LKRLDLT------------GCWSLVEIPSSVG 702

  Fly   168 RLNNVAVLLRNYRITELVSLDLAYNDLKQLDQFPEGF--SSIRSLQL----QSNELPSLPDNFF- 225
            .|:.:.              :|..|...||...|..|  :|:|||::    :..:.|.:..|..
plant   703 NLHKLE--------------ELEMNLCLQLQVVPTHFNLASLRSLRMLGCWELRKFPGISTNITS 753

  Fly   226 -----AVTHARLETLNV-SCNKLSTLPRYEQNNHAALVNLSLAGNHLNDSIFEPLHNAAKLRVLH 284
                 |:....||::.: ||  |.||..|              |:.:.       ||...:.::.
plant   754 LVIGDAMLEEMLESIRLWSC--LETLVVY--------------GSVIT-------HNFWAVTLIE 795

  Fly   285 LAYNRIGVLPAACVRNWPELEILVLSG-NMLQQLPEEVATLGQLRVLRC 332
            .....|..:| .|:::.|.|:.|.:.| ..|..|||...:|.:|.|..|
plant   796 KMGTDIERIP-DCIKDLPALKSLYIGGCPKLFSLPELPGSLRRLTVETC 843

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Phlpp	NP_001260558.1	leucine-rich repeat	91..110	CDD:275380	6/20 (30%)
		LRR_8	109..169	CDD:290566	10/59 (17%)
		leucine-rich repeat	111..135	CDD:275380	0/23 (0%)
		leucine-rich repeat	136..158	CDD:275380	4/21 (19%)
		leucine-rich repeat	159..183	CDD:275380	4/23 (17%)
		leucine-rich repeat	184..209	CDD:275380	7/26 (27%)
		LRR_8	205..266	CDD:290566	16/71 (23%)
		leucine-rich repeat	210..230	CDD:275380	4/29 (14%)
		leucine-rich repeat	232..255	CDD:275380	8/23 (35%)
		LRR_RI	<256..410	CDD:238064	18/78 (23%)
		leucine-rich repeat	256..276	CDD:275380	1/19 (5%)
		LRR_8	279..359	CDD:290566	15/55 (27%)
		leucine-rich repeat	280..303	CDD:275380	3/22 (14%)
		leucine-rich repeat	304..348	CDD:275380	11/30 (37%)
		leucine-rich repeat	349..372	CDD:275380
		PP2Cc	461..655	CDD:294085
AT1G63740	NP_001322890.1	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X32
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000