DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Phlpp and AT5G58120

DIOPT Version :9

Sequence 1:	NP_001260558.1	Gene:	Phlpp / 35178	FlyBaseID:	FBgn0032749	Length:	954	Species:	Drosophila melanogaster
Sequence 2:	NP_200620.1	Gene:	AT5G58120 / 835924	AraportID:	AT5G58120	Length:	1046	Species:	Arabidopsis thaliana

Alignment Length:	280	Identity:	60/280 - (21%)
Similarity:	109/280 - (38%)	Gaps:	65/280 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    66 NYNYLTQLEVCENEMEVL--DLSSLAQLETLKCSRN-KLMEL--IINGTNLQTLVADHNYLHNIS 125
            |..:|.:|.:..:::|.|  ...||..|:.:....: .|.||  :.|.|||:.|        |::
plant   601 NPEFLVELNMQGSQLEHLWSGTQSLRNLKNMDLGWSPNLKELPDLTNATNLEDL--------NLN 657

  Fly   126 TTNTHPVPLKLQRIDISHNNFSELPN-WVGACASLTAINASHNRLNNVAVLL---RNYRITELVS 186
            :..:      |..|..|.::..:|.| |:..|.:|..|.|..|.::...|.:   ..:|...::|
plant   658 SCES------LVEIPSSFSHLHKLKNLWMSYCINLQVIPAHMNLVSLERVTMTGCSRFRKIPVIS 716

  Fly   187 LDLAYNDLKQLDQFPEGFSSI------RSLQLQSNELPSLPDNFFAVTHA--------------- 230
            ..:.|.|:....:|....:||      ..|.:..||      ||..:||.
plant   717 THINYLDIAHNTEFEVVHASIALWCRLHYLNMSYNE------NFMGLTHLPMSLTQLILRYSDIE 775

  Fly   231 ----------RLETLNVS-CNKLSTLPRYEQNNHAALVNLSLAGNHLNDSIFEPLHNAAKLRVLH 284
                      :|.:|::: |.:|::||...    .:|::|........:::|.|||....|....
plant   776 RIPDCIKALHQLFSLDLTGCRRLASLPELP----GSLLDLEAEDCESLETVFSPLHTPRALLNFT 836

  Fly   285 LAYNRIGVLPAACVRNWPEL 304
            ..:...|....|.:|...|:
plant   837 NCFKLGGQARRAIIRRRSEI 856

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Phlpp	NP_001260558.1	leucine-rich repeat	91..110	CDD:275380	5/21 (24%)
		LRR_8	109..169	CDD:290566	16/60 (27%)
		leucine-rich repeat	111..135	CDD:275380	3/23 (13%)
		leucine-rich repeat	136..158	CDD:275380	7/22 (32%)
		leucine-rich repeat	159..183	CDD:275380	6/26 (23%)
		leucine-rich repeat	184..209	CDD:275380	6/30 (20%)
		LRR_8	205..266	CDD:290566	17/92 (18%)
		leucine-rich repeat	210..230	CDD:275380	6/19 (32%)
		leucine-rich repeat	232..255	CDD:275380	6/23 (26%)
		LRR_RI	<256..410	CDD:238064	11/49 (22%)
		leucine-rich repeat	256..276	CDD:275380	5/19 (26%)
		LRR_8	279..359	CDD:290566	5/26 (19%)
		leucine-rich repeat	280..303	CDD:275380	4/22 (18%)
		leucine-rich repeat	304..348	CDD:275380	0/1 (0%)
		leucine-rich repeat	349..372	CDD:275380
		PP2Cc	461..655	CDD:294085
AT5G58120	NP_200620.1	PLN03210	12..1040	CDD:215633	60/280 (21%)
		leucine-rich repeat	605..627	CDD:275380	6/21 (29%)
		leucine-rich repeat	628..650	CDD:275380	5/21 (24%)
		leucine-rich repeat	651..674	CDD:275380	6/36 (17%)
		leucine-rich repeat	675..697	CDD:275380	8/21 (38%)
		leucine-rich repeat	698..718	CDD:275380	3/19 (16%)
		leucine-rich repeat	719..742	CDD:275380	5/22 (23%)
		leucine-rich repeat	764..786	CDD:275380	0/21 (0%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X32
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000