DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Phlpp and AT5G46520

DIOPT Version :9

Sequence 1:	NP_001260558.1	Gene:	Phlpp / 35178	FlyBaseID:	FBgn0032749	Length:	954	Species:	Drosophila melanogaster
Sequence 2:	NP_001330914.1	Gene:	AT5G46520 / 834695	AraportID:	AT5G46520	Length:	1206	Species:	Arabidopsis thaliana

Alignment Length:	368	Identity:	86/368 - (23%)
Similarity:	134/368 - (36%)	Gaps:	111/368 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly    85 LSSLAQLETLKCSRNKLMELIINGTNLQTL-VADHNYLHNI----STTNTHPVPLKLQRIDISHN 144
            |.:|.:||.......||.|..::.|.|:.| :....||..|    ..||       ::::|..|
plant   644 LRNLVKLEMHDSKLEKLWEGAMSFTCLKELDMWASKYLKEIPDLSKATN-------IEKLDFGH- 700

  Fly   145 NFSELPNWVGACASLTAINASHNRLNNVAVLLRNYRITELVSLDLAYNDLKQLD----------- 198
                       |.||..:.:|...||.:..|...| ..||.:|...:| ||.||
plant   701 -----------CWSLVELPSSIRNLNKLLELNMEY-CGELETLPTGFN-LKSLDYLNFNECWKLR 752

  Fly   199 QFPEGFSSIRSLQLQSNELPSLPDNFF-----AVTHARLETLNVSCNKLS--------TLPRYEQ 250
            .|||..::|.:|.|....:...|.|.:     .::..:.::....|..:.        ||...|.
plant   753 TFPEFATNISNLILAETSIEEYPSNLYFKNVRELSMGKADSDENKCQGVKPFMPMLSPTLTLLEL 817

  Fly   251 NNHAALVNLSLAGNHLNDSIFEPLHNAAKLRVLHLAYNRIGVLPAACVRNWPELEILVLSGNMLQ 315
            .|...||.||        |.|:.|:|..:|.:.:            | ||   ||.|....|:
plant   818 WNIPNLVELS--------SSFQNLNNLERLDICY------------C-RN---LESLPTGINL-- 856

  Fly   316 QLPEEVATLGQLRVLRCCNNLLLCT-----PQLAKLAMLKVLDLSHNHLDRV--------NL--L 365
               |.:.:|          ||..|:     |.::  ..:|.|||....::.|        ||  |
plant   857 ---ESLVSL----------NLFGCSRLKRFPDIS--TNIKYLDLDQTGIEEVPWQIENFFNLTKL 906

  Fly   366 ALVPSRNLKYLDLSGNLQLQVDEQQFKVCQSQSQRHWSLVDVS 408
            .:...|.||.:.|:......:.|..|..|.:.::     ||:|
plant   907 TMKGCRELKCVSLNIFKLKHLGEVSFSNCGALTR-----VDLS 944

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Phlpp	NP_001260558.1	leucine-rich repeat	91..110	CDD:275380	5/18 (28%)
		LRR_8	109..169	CDD:290566	14/64 (22%)
		leucine-rich repeat	111..135	CDD:275380	7/28 (25%)
		leucine-rich repeat	136..158	CDD:275380	3/21 (14%)
		leucine-rich repeat	159..183	CDD:275380	6/23 (26%)
		leucine-rich repeat	184..209	CDD:275380	11/35 (31%)
		LRR_8	205..266	CDD:290566	14/73 (19%)
		leucine-rich repeat	210..230	CDD:275380	4/24 (17%)
		leucine-rich repeat	232..255	CDD:275380	5/30 (17%)
		LRR_RI	<256..410	CDD:238064	40/168 (24%)
		leucine-rich repeat	256..276	CDD:275380	7/19 (37%)
		LRR_8	279..359	CDD:290566	18/84 (21%)
		leucine-rich repeat	280..303	CDD:275380	4/22 (18%)
		leucine-rich repeat	304..348	CDD:275380	10/48 (21%)
		leucine-rich repeat	349..372	CDD:275380	8/32 (25%)
		PP2Cc	461..655	CDD:294085
AT5G46520	NP_001330914.1	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X32
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000