DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Phlpp and AT5G46510

DIOPT Version :9

Sequence 1:	NP_001260558.1	Gene:	Phlpp / 35178	FlyBaseID:	FBgn0032749	Length:	954	Species:	Drosophila melanogaster
Sequence 2:	NP_199463.1	Gene:	AT5G46510 / 834694	AraportID:	AT5G46510	Length:	1353	Species:	Arabidopsis thaliana

Alignment Length:	373	Identity:	85/373 - (22%)
Similarity:	133/373 - (35%)	Gaps:	121/373 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly    85 LSSLAQLETLKCSRNKLMELIINGTNLQTL-VADHNYLHNI----STTNTHPVPLKLQRIDISHN 144
            |.:|.:||.......||.|..::.|.|:.| :....||..|    ..||       ::::|..|
plant   605 LRNLVKLEMHDSKLEKLWEGAMSFTCLKELDMWASKYLKEIPDLSKATN-------IEKLDFGH- 661

  Fly   145 NFSELPNWVGACASLTAINASHNRLNNVAVLLRNYRITELVSLDLAYNDLKQLD----------- 198
                       |.||..:.:|...||.:..|...| ..||.:|...:| ||.||
plant   662 -----------CWSLVELPSSIRNLNKLLELNMEY-CGELETLPTGFN-LKSLDYLNFNECWKLR 713

  Fly   199 QFPEGFSSIRSLQLQSNELPSLPDNFF-----AVTHARLETLNVSCNKLS--------TLPRYEQ 250
            .|||..::|.:|.|....:...|.|.:     .::..:.::....|..:.        ||...|.
plant   714 TFPEFATNISNLILAETSIEEYPSNLYFKNVRELSMGKADSDENKCQGVKPFMPMLSPTLTLLEL 778

  Fly   251 NNHAALVNLSLAGNHLNDSIFEPLHNAAKLRVLHLAYNRIGVLPAACVRNWPELEILVLSGNMLQ 315
            .|...||.||        |.|:.|:|..:|.:.:            | ||             |:
plant   779 WNIPNLVELS--------SSFQNLNNLERLDICY------------C-RN-------------LE 809

  Fly   316 QLP-----EEVATLGQLRVLRCCNNLLLCT-----PQLAKLAMLKVLDLSHNHLDRV-------- 362
            .||     |.:.:|          ||..|:     |.::  ..:|.|||....::.|
plant   810 SLPTGINLESLVSL----------NLFGCSRLKRFPDIS--TNIKYLDLDQTGIEEVPWQIENFF 862

  Fly   363 NL--LALVPSRNLKYLDLSGNLQLQVDEQQFKVCQSQSQRHWSLVDVS 408
            ||  |.:...|.||.:.|:......:.|..|..|.:.::     ||:|
plant   863 NLTKLTMKGCRELKCVSLNIFKLKHLGEVSFSNCGALTR-----VDLS 905

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Phlpp	NP_001260558.1	leucine-rich repeat	91..110	CDD:275380	5/18 (28%)
		LRR_8	109..169	CDD:290566	14/64 (22%)
		leucine-rich repeat	111..135	CDD:275380	7/28 (25%)
		leucine-rich repeat	136..158	CDD:275380	3/21 (14%)
		leucine-rich repeat	159..183	CDD:275380	6/23 (26%)
		leucine-rich repeat	184..209	CDD:275380	11/35 (31%)
		LRR_8	205..266	CDD:290566	14/73 (19%)
		leucine-rich repeat	210..230	CDD:275380	4/24 (17%)
		leucine-rich repeat	232..255	CDD:275380	5/30 (17%)
		LRR_RI	<256..410	CDD:238064	39/173 (23%)
		leucine-rich repeat	256..276	CDD:275380	7/19 (37%)
		LRR_8	279..359	CDD:290566	17/89 (19%)
		leucine-rich repeat	280..303	CDD:275380	4/22 (18%)
		leucine-rich repeat	304..348	CDD:275380	9/53 (17%)
		leucine-rich repeat	349..372	CDD:275380	8/32 (25%)
		PP2Cc	461..655	CDD:294085
AT5G46510	NP_199463.1	PLN03210	2..1165	CDD:215633	85/373 (23%)
		TIR	9..173	CDD:279864
		NK	206..264	CDD:238977
		leucine-rich repeat	557..586	CDD:275380
		leucine-rich repeat	587..607	CDD:275380	1/1 (100%)
		LRR_3	607..624	CDD:285026	5/16 (31%)
		leucine-rich repeat	608..630	CDD:275380	6/21 (29%)
		leucine-rich repeat	631..653	CDD:275380	5/21 (24%)
		leucine-rich repeat	655..677	CDD:275380	7/33 (21%)
		leucine-rich repeat	678..700	CDD:275380	7/23 (30%)
		leucine-rich repeat	701..721	CDD:275380	5/19 (26%)
		leucine-rich repeat	722..743	CDD:275380	5/20 (25%)
		leucine-rich repeat	773..796	CDD:275378	10/30 (33%)
		leucine-rich repeat	797..819	CDD:275378	7/47 (15%)
		leucine-rich repeat	820..840	CDD:275378	5/31 (16%)
		leucine-rich repeat	841..866	CDD:275378	7/24 (29%)
		leucine-rich repeat	873..898	CDD:275380	7/24 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X32
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000