DRSC/TRiP Functional Genomics Resources

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Protein Alignment Phlpp and RPS6

DIOPT Version :9

Sequence 1:NP_001260558.1 Gene:Phlpp / 35178 FlyBaseID:FBgn0032749 Length:954 Species:Drosophila melanogaster
Sequence 2:NP_199459.2 Gene:RPS6 / 834690 AraportID:AT5G46470 Length:1127 Species:Arabidopsis thaliana


Alignment Length:439 Identity:105/439 - (23%)
Similarity:170/439 - (38%) Gaps:147/439 - (33%)


- Green bases have known domain annotations that are detailed below.


  Fly    50 KLSLKGSQL-----GGSILIGNYNYLTQLEVCENEMEVLDLSSLAQLETLKCSR-NKLMELIING 108
            ||.::.|:|     |...|.|..|  ..|....|..|:.|||....|||||.|. :.|:||   .
plant   614 KLQMQQSKLEKLWDGVHSLAGLRN--MDLRGSRNLKEIPDLSMATNLETLKLSSCSSLVEL---P 673

  Fly   109 TNLQTL----VADHNYLHNISTTNTHPVPLK-LQRIDISH----NNFSELP---NW--VGACASL 159
            :::|.|    ..|.:|..::.|..: .|.|| |.|:::|.    .:|.::|   :|  :|..|.:
plant   674 SSIQYLNKLNDLDMSYCDHLETIPS-GVNLKSLDRLNLSGCSRLKSFLDIPTNISWLDIGQTADI 737

  Fly   160 TAINASHNRLNNVAVLLRNYRI---TELVSLDLAYNDLKQLDQFPEGFSSIRSLQLQSN----EL 217
                .|:.||.|:..|:...|:   |.|::: |:              .::..|...:|    |:
plant   738 ----PSNLRLQNLDELILCERVQLRTPLMTM-LS--------------PTLTRLTFSNNPSFVEV 783

  Fly   218 PSLPDNFFAVTHARLETLNVSCNKLSTLPRYEQNNHAALVNLSLAGNHLNDSIFEPLHNAAKLRV 282
            ||...|.:.:.|  ||.:|  |..|.|||               .|.:|:..|...|.:.::|  
plant   784 PSSIQNLYQLEH--LEIMN--CRNLVTLP---------------TGINLDSLISLDLSHCSQL-- 827

  Fly   283 LHLAYNRIGVLPAACVRNWPELEI----LVLSGNMLQQLPEEVATLGQLRVL--RCCNNLLLCTP 341
                            :.:|::..    |.||...::::|..:..|..|..|  ..|:|||..:|
plant   828 ----------------KTFPDISTNISDLNLSYTAIEEVPLSIEKLSLLCYLDMNGCSNLLCVSP 876

  Fly   342 QLAKLAMLKVLDLSHNHLDRVNL------------LALVPSRNLK----------YLDLSGNLQL 384
            .::||..|:..|.|    |.|.|            :.|:|:.|..          .|||:..:|.
plant   877 NISKLKHLERADFS----DCVELTEASWNGSSSEMVKLLPADNFSTVKLNFINCFKLDLTALIQN 937

  Fly   385 Q-------------------------VDEQQFKVCQS-QSQRHWSLVDV 407
            |                         :......|||| .|.|..:::||
plant   938 QTFFMQLILTGEEVPSYFTHRTSGDSISLPHISVCQSFFSFRGCTVIDV 986

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
PhlppNP_001260558.1 leucine-rich repeat 91..110 CDD:275380 9/19 (47%)
LRR_8 109..169 CDD:290566 17/73 (23%)
leucine-rich repeat 111..135 CDD:275380 6/27 (22%)
leucine-rich repeat 136..158 CDD:275380 7/30 (23%)
leucine-rich repeat 159..183 CDD:275380 6/26 (23%)
leucine-rich repeat 184..209 CDD:275380 2/24 (8%)
LRR_8 205..266 CDD:290566 16/64 (25%)
leucine-rich repeat 210..230 CDD:275380 6/23 (26%)
leucine-rich repeat 232..255 CDD:275380 8/22 (36%)
LRR_RI <256..410 CDD:238064 42/206 (20%)
leucine-rich repeat 256..276 CDD:275380 4/19 (21%)
LRR_8 279..359 CDD:290566 19/85 (22%)
leucine-rich repeat 280..303 CDD:275380 1/22 (5%)
leucine-rich repeat 304..348 CDD:275380 14/49 (29%)
leucine-rich repeat 349..372 CDD:275380 8/34 (24%)
PP2Cc 461..655 CDD:294085
RPS6NP_199459.2 PLN03210 10..1111 CDD:215633 105/439 (24%)
TIR 14..179 CDD:279864
AAA_16 187..>232 CDD:289934
LRR_3 611..629 CDD:285026 4/14 (29%)
leucine-rich repeat 612..634 CDD:275380 6/19 (32%)
leucine-rich repeat 635..657 CDD:275380 7/23 (30%)
leucine-rich repeat 658..681 CDD:275380 11/25 (44%)
leucine-rich repeat 682..704 CDD:275380 5/22 (23%)
leucine-rich repeat 705..725 CDD:275380 5/19 (26%)
leucine-rich repeat 726..745 CDD:275380 6/22 (27%)
leucine-rich repeat 746..768 CDD:275380 5/36 (14%)
leucine-rich repeat 769..792 CDD:275380 6/22 (27%)
leucine-rich repeat 793..815 CDD:275380 11/40 (28%)
leucine-rich repeat 860..883 CDD:275381 9/22 (41%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
SonicParanoid 1 1.000 - - X32
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
11.000

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