DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Phlpp and AT5G45210

DIOPT Version :9

Sequence 1:	NP_001260558.1	Gene:	Phlpp / 35178	FlyBaseID:	FBgn0032749	Length:	954	Species:	Drosophila melanogaster
Sequence 2:	NP_001332330.1	Gene:	AT5G45210 / 834557	AraportID:	AT5G45210	Length:	725	Species:	Arabidopsis thaliana

Alignment Length:	438	Identity:	82/438 - (18%)
Similarity:	152/438 - (34%)	Gaps:	163/438 - (37%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 PYKSKL----KVSASHSGPHP--------------LPVEVTAAEEEQAATFGQTSPQKLSLKGSQ 57
            |..:||    |..|.::|.:|              .|.|:    ||:.....|..||::.
plant   369 PSDAKLMDVSKKVARYAGGNPKALCFYGRELEKKKKPEEM----EEEFEKMRQCPPQEIL----- 424

  Fly    58 LGGSILIGNYNYLTQL--------------EVCENEMEVLD---------LSSLAQLETLKCSRN 99
               |:...:|:.|...              |.|::.|.:|:         :..||:...|..|:.
plant   425 ---SLFRSSYDALNDNERSIFLDIACFFNGEPCDDVMRILEGCGFFPHVGIDRLAERSLLTISKE 486

  Fly   100 KLMELIINGTNLQTLVAD--HNYLHNISTTNTHPVPLKLQRIDISHNNFSELPNWVGACASLTAI 162
            |.:|       :|..:.|  ..:::..|....|..|.:::.:                      :
plant   487 KRVE-------MQGFIQDAAREFINQTSRRRRHWEPSRIRLL----------------------L 522

  Fly   163 NASHNRLNNV--AVLLRNYRIT---ELVSLDLAYNDLKQLDQFPEGFSSIRSLQLQSNELPSLPD 222
            ....::.|.|  .:.|...::|   ..::.:..|| |:.|..:.....:.:.|:| :.||.|||
plant   523 ENDKSKGNEVIEGIFLDTTKLTFDVNPMAFENMYN-LRLLKIYSTHSETAQELRL-TKELRSLP- 584

  Fly   223 NFFAVTHARLETLNVSCNKLSTLPRYEQNNHAALVNLSLAGNHLNDSIFEPLHNAAKLRVLHLAY 287
                   ..|..|:.....|.:||:.....|  ||.|::..:.| .|:.....:.|||::::|::
plant   585 -------YELRLLHWEKYPLQSLPQDFDTRH--LVELNMPYSQL-QSLCVGTKSLAKLKMINLSH 639

  Fly   288 NRIGVLPAACVRNWPELEILVLSGNMLQQLPEEVATLGQLRVLRCCNNLLLCTPQLAKLAMLKVL 352
            ::                                              .||...:|||...|:.:
plant   640 SQ----------------------------------------------KLLEVDELAKACNLEKI 658

  Fly   353 DL-------SHNHLDRVNLLALVPSRNLKYLDLSGNLQLQVDEQQFKV 393
            ||       |..|.||:        :||::|:|||...::..|...|:
plant   659 DLQGCTSLKSIPHTDRL--------KNLQFLNLSGCTSIKRTEAIKKI 698

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Phlpp	NP_001260558.1	leucine-rich repeat	91..110	CDD:275380	4/18 (22%)
		LRR_8	109..169	CDD:290566	5/61 (8%)
		leucine-rich repeat	111..135	CDD:275380	5/25 (20%)
		leucine-rich repeat	136..158	CDD:275380	0/21 (0%)
		leucine-rich repeat	159..183	CDD:275380	4/28 (14%)
		leucine-rich repeat	184..209	CDD:275380	4/24 (17%)
		LRR_8	205..266	CDD:290566	16/60 (27%)
		leucine-rich repeat	210..230	CDD:275380	7/19 (37%)
		leucine-rich repeat	232..255	CDD:275380	6/22 (27%)
		LRR_RI	<256..410	CDD:238064	29/145 (20%)
		leucine-rich repeat	256..276	CDD:275380	5/19 (26%)
		LRR_8	279..359	CDD:290566	12/86 (14%)
		leucine-rich repeat	280..303	CDD:275380	2/22 (9%)
		leucine-rich repeat	304..348	CDD:275380	5/43 (12%)
		leucine-rich repeat	349..372	CDD:275380	7/29 (24%)
		PP2Cc	461..655	CDD:294085
AT5G45210	NP_001332330.1	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X32
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000