DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Phlpp and AT5G38850

DIOPT Version :9

Sequence 1:	NP_001260558.1	Gene:	Phlpp / 35178	FlyBaseID:	FBgn0032749	Length:	954	Species:	Drosophila melanogaster
Sequence 2:	NP_198701.1	Gene:	AT5G38850 / 833876	AraportID:	AT5G38850	Length:	986	Species:	Arabidopsis thaliana

Alignment Length:	260	Identity:	65/260 - (25%)
Similarity:	118/260 - (45%)	Gaps:	41/260 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 LKATRKQADPYKS-KLKVSASHSGPHPLPVEVTAAEEEQAATFGQTSPQKLSLKGS-QLGGSILI 64
            |:..:.:|.|.:| .||::..:.  ..|.:|.:..|:....|....:.:|:||..| .|.....:
plant   571 LRLLQWEAYPRRSLSLKLNLEYL--VELDMEGSLLEKLWDGTQPLANLKKMSLSSSWYLKKLPDL 633

  Fly    65 GNYNYLTQLEV--CENEMEVLDLSSLAQLETLK------CSRNKLMELIINGTNLQTLVADHNYL 121
            .|...|.:|::  |:|.:|:  .||.:.|..||      |.|.|.:...||..:|:.:     .:
plant   634 SNATNLEELDLRACQNLVEL--PSSFSYLHKLKYLNMMGCRRLKEVPPHINLKSLELV-----NM 691

  Fly   122 HNISTTNTHP-VPLKLQRIDISHNNFSELPNWVGACASLTAINASHNRLNNVAVL-LRNYRITEL 184
            :..|...:.| :...:..:|||:.:..|||.      |:|    ..:||..:.:. .||.:|...
plant   692 YGCSRLKSFPDISTNISSLDISYTDVEELPE------SMT----MWSRLRTLEIYKSRNLKIVTH 746

  Fly   185 VSLDLAYNDLKQ--LDQFPEGFSSIRSLQL-------QSNELPSLPDNFFAVTHARLETL-NVSC 239
            |.|:|.|.||.:  :::.|:...::..||:       :...||.||.:...::....|:| :|||
plant   747 VPLNLTYLDLSETRIEKIPDDIKNVHGLQILFLGGCRKLASLPELPGSLLYLSANECESLESVSC 811

Fly 240 239
plant 812 811

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Phlpp	NP_001260558.1	leucine-rich repeat	91..110	CDD:275380	8/24 (33%)
		LRR_8	109..169	CDD:290566	11/60 (18%)
		leucine-rich repeat	111..135	CDD:275380	3/24 (13%)
		leucine-rich repeat	136..158	CDD:275380	6/21 (29%)
		leucine-rich repeat	159..183	CDD:275380	6/24 (25%)
		leucine-rich repeat	184..209	CDD:275380	7/26 (27%)
		LRR_8	205..266	CDD:290566	11/43 (26%)
		leucine-rich repeat	210..230	CDD:275380	6/26 (23%)
		leucine-rich repeat	232..255	CDD:275380	5/9 (56%)
		LRR_RI	<256..410	CDD:238064
		leucine-rich repeat	256..276	CDD:275380
		LRR_8	279..359	CDD:290566
		leucine-rich repeat	280..303	CDD:275380
		leucine-rich repeat	304..348	CDD:275380
		leucine-rich repeat	349..372	CDD:275380
		PP2Cc	461..655	CDD:294085
AT5G38850	NP_198701.1	PLN03210	2..973	CDD:215633	65/260 (25%)
		leucine-rich repeat	543..576	CDD:275380	1/4 (25%)
		leucine-rich repeat	593..615	CDD:275380	4/23 (17%)
		leucine-rich repeat	616..638	CDD:275380	6/21 (29%)
		leucine-rich repeat	639..662	CDD:275380	8/24 (33%)
		leucine-rich repeat	663..685	CDD:275380	7/21 (33%)
		leucine-rich repeat	686..706	CDD:275380	3/24 (13%)
		leucine-rich repeat	707..732	CDD:275380	10/34 (29%)
		leucine-rich repeat	751..773	CDD:275380	5/21 (24%)
		leucine-rich repeat	774..794	CDD:275380	6/19 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X32
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000