DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Phlpp and AT5G22690

DIOPT Version :9

Sequence 1:	NP_001260558.1	Gene:	Phlpp / 35178	FlyBaseID:	FBgn0032749	Length:	954	Species:	Drosophila melanogaster
Sequence 2:	NP_001331342.1	Gene:	AT5G22690 / 832332	AraportID:	AT5G22690	Length:	1010	Species:	Arabidopsis thaliana

Alignment Length:	376	Identity:	81/376 - (21%)
Similarity:	156/376 - (41%)	Gaps:	71/376 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    50 KLSLKGSQLGGSILIGNYNYLTQLEVCENEMEVLDLSSLAQLETLKCSRNKLM------ELIING 108
            ||.|..|.||.:|.:.|   |....:.....:.:::.|:.|....:..|.:.:      |.:::.
plant   456 KLLLADSNLGVTIGLKN---LVDKSLIRIGCDTVEMHSMLQEMGREIVREQSIYEPGEREFLVDS 517

  Fly   109 TNLQTLVADHNYLHNISTTNTHPVPLKLQRIDISH---NNFSELPNW--------VGACASLTAI 162
            |::..::.|     |..|.....:...:..|:..|   ..|..:||.        :|..:....:
plant   518 TDILDVLND-----NTGTKKVLGISFDMSEIEELHIHKRAFKRMPNLRFLRFYKKLGKQSKEARL 577

  Fly   163 NASHN-------RLNNVA-------VLLRNYRITELVSLDLAYNDLKQLDQFPEGFSSIRSLQL- 212
            :....       :|..::       .:..|:....||.|.:.::.|::|.|..:..:.:|.:||
plant   578 HLQEGFDKFFPPKLKLLSWDDYPMRRMPSNFHAGYLVVLRMQHSKLEKLWQGVQPLTCLREMQLW 642

  Fly   213 QSNELPSLPDNFFAVTHARLETLNVS-CNKLSTLPRYEQNNHAALVNLSLAGNHLNDSIFEPLHN 276
            .|.:|..:||...|   ..||||.:: |:.|..||...:|.: .|.:|.:.|
plant   643 GSKKLKEIPDLSLA---TNLETLYLNDCSSLVELPSSIKNLN-KLWDLGMKG------------- 690

  Fly   277 AAKLRVLHLAYN-----RIGVLPAACVRNWPELEI----LVLSGNMLQQLPEEVATLGQLRVLRC 332
            ..||.:|....|     |:.:...:.::::|::..    |.|:...::::|..:....:|:.||.
plant   691 CEKLELLPTDINLKSLYRLDLGRCSRLKSFPDISSNISELYLNRTAIEEVPWWIQKFSRLKRLRM 755

  Fly   333 --CNNLLLCTPQLAKLAMLKVLDLSHNHLDRVNLLALVPSRN-LKYLDLSG 380
              |..|...:|.::||..|::||.| |.:......|||..:: ||||...|
plant   756 RECKKLKCISPNISKLKHLEMLDFS-NCIATTEEEALVQQQSVLKYLIFPG 805

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Phlpp	NP_001260558.1	leucine-rich repeat	91..110	CDD:275380	2/24 (8%)
		LRR_8	109..169	CDD:290566	10/77 (13%)
		leucine-rich repeat	111..135	CDD:275380	3/23 (13%)
		leucine-rich repeat	136..158	CDD:275380	6/32 (19%)
		leucine-rich repeat	159..183	CDD:275380	2/37 (5%)
		leucine-rich repeat	184..209	CDD:275380	6/24 (25%)
		LRR_8	205..266	CDD:290566	20/62 (32%)
		leucine-rich repeat	210..230	CDD:275380	7/20 (35%)
		leucine-rich repeat	232..255	CDD:275380	9/23 (39%)
		LRR_RI	<256..410	CDD:238064	33/137 (24%)
		leucine-rich repeat	256..276	CDD:275380	3/19 (16%)
		LRR_8	279..359	CDD:290566	22/90 (24%)
		leucine-rich repeat	280..303	CDD:275380	4/27 (15%)
		leucine-rich repeat	304..348	CDD:275380	11/49 (22%)
		leucine-rich repeat	349..372	CDD:275380	8/22 (36%)
		PP2Cc	461..655	CDD:294085
AT5G22690	NP_001331342.1	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X32
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000