DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Phlpp and AT5G17970

DIOPT Version :9

Sequence 1:	NP_001260558.1	Gene:	Phlpp / 35178	FlyBaseID:	FBgn0032749	Length:	954	Species:	Drosophila melanogaster
Sequence 2:	NP_197298.1	Gene:	AT5G17970 / 831664	AraportID:	AT5G17970	Length:	780	Species:	Arabidopsis thaliana

Alignment Length:	305	Identity:	68/305 - (22%)
Similarity:	122/305 - (40%)	Gaps:	79/305 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   103 ELIINGTNLQTLVADHNYLHNISTTNTHPVPLKLQRID----ISHNNFSELPN----WVGACASL 159
            :.:::...:..::||..     .|.....:.|.:..|:    :|...|.::||    |
plant   517 KFLVDSLEISDVLADET-----GTETVLGISLDMSEIEDQVYVSEKAFEKMPNLQFLW------- 569

  Fly   160 TAINASHNRLNNVAVLLRNYRITELVSLDLAYNDLKQLDQFPEGFSSIRSLQLQSNELPSLPDNF 224
                           |.:|:. .|.|.|.|.:.    ||..|.   .:|.|...|.....||..|
plant   570 ---------------LYKNFP-DEAVKLYLPHG----LDYLPR---KLRLLHWDSYPKKCLPSKF 611

  Fly   225 -------FAVTHARLETLNVSCNKLSTLPRYEQNNHAALVNLSLAGNHLNDSIFEPLHNAAKLRV 282
                   ..:..::||.|......|.:|.|         ::|| |...:.|  ...|..|..|..
plant   612 RPEFLVELTMRDSKLEKLWEGIQPLKSLKR---------MDLS-ASTKIKD--IPNLSRATNLEK 664

  Fly   283 LHLAY-NRIGVLPAACVRNWPELEILVLSGNM-LQQLPEEVATLGQLRVL--RCC---NNLLLCT 340
            |:|.: ..:.::|::|::|..:|::|.:|..: |:.||:.: .|..|.||  |.|   ||..|.:
plant   665 LYLRFCKNLVIVPSSCLQNLHKLKVLDMSCCIKLKSLPDNI-NLKSLSVLNMRGCSKLNNFPLIS 728

  Fly   341 PQLAKLAMLKVLDLSHNHLDRVNLLALVPSRNLKYLDLSG--NLQ 383
            .|      ::.:.|....:::|..:..:.|| |..|:::|  ||:
plant   729 TQ------IQFMSLGETAIEKVPSVIKLCSR-LVSLEMAGCKNLK 766

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Phlpp	NP_001260558.1	leucine-rich repeat	91..110	CDD:275380	0/6 (0%)
		LRR_8	109..169	CDD:290566	10/67 (15%)
		leucine-rich repeat	111..135	CDD:275380	3/23 (13%)
		leucine-rich repeat	136..158	CDD:275380	6/29 (21%)
		leucine-rich repeat	159..183	CDD:275380	2/23 (9%)
		leucine-rich repeat	184..209	CDD:275380	6/24 (25%)
		LRR_8	205..266	CDD:290566	15/67 (22%)
		leucine-rich repeat	210..230	CDD:275380	5/26 (19%)
		leucine-rich repeat	232..255	CDD:275380	6/22 (27%)
		LRR_RI	<256..410	CDD:238064	37/137 (27%)
		leucine-rich repeat	256..276	CDD:275380	5/19 (26%)
		LRR_8	279..359	CDD:290566	23/86 (27%)
		leucine-rich repeat	280..303	CDD:275380	6/23 (26%)
		leucine-rich repeat	304..348	CDD:275380	16/49 (33%)
		leucine-rich repeat	349..372	CDD:275380	3/22 (14%)
		PP2Cc	461..655	CDD:294085
AT5G17970	NP_197298.1	PLN03210	16..>766	CDD:215633	67/303 (22%)
		leucine-rich repeat	565..593	CDD:275380	10/57 (18%)
		leucine-rich repeat	594..615	CDD:275380	6/20 (30%)
		leucine-rich repeat	616..638	CDD:275380	4/21 (19%)
		leucine-rich repeat	639..661	CDD:275380	8/33 (24%)
		leucine-rich repeat	662..686	CDD:275380	6/23 (26%)
		leucine-rich repeat	687..709	CDD:275380	7/22 (32%)
		leucine-rich repeat	731..753	CDD:275381	2/21 (10%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X32
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000