DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Phlpp and AT5G17680

DIOPT Version :9

Sequence 1:	NP_001260558.1	Gene:	Phlpp / 35178	FlyBaseID:	FBgn0032749	Length:	954	Species:	Drosophila melanogaster
Sequence 2:	NP_001331467.1	Gene:	AT5G17680 / 831634	AraportID:	AT5G17680	Length:	1295	Species:	Arabidopsis thaliana

Alignment Length:	374	Identity:	95/374 - (25%)
Similarity:	158/374 - (42%)	Gaps:	82/374 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    73 LEVCENEMEVLDLSSLAQLETLKCSR-NKLMELIINGTNLQTLVADHNYLHN------------- 123
            |..|:..:||.|||....||.|..|. ..|:|:..:..||:.|..  .||.|
plant   633 LSRCKYLVEVPDLSKATNLEELNLSYCQSLVEVTPSIKNLKGLSC--FYLTNCIQLKDIPIGIIL 695

  Fly   124 ----------------------------ISTTNTHPVPLKLQR------IDISH-NNFSELPNWV 153
                                        :|:|....:|..:.|      :|:|. .....||:::
plant   696 KSLETVGMSGCSSLKHFPEISWNTRRLYLSSTKIEELPSSISRLSCLVKLDMSDCQRLRTLPSYL 760

  Fly   154 GACASLTAINASH-NRLNNVAVLLRNYRITELVSLDLAYNDLKQLDQFPEGFSSIRSLQLQSNEL 217
            |...||.::|... .||.|:...|:|  :|.|.:|::  :....:::||...:||..|::....:
plant   761 GHLVSLKSLNLDGCRRLENLPDTLQN--LTSLETLEV--SGCLNVNEFPRVSTSIEVLRISETSI 821

  Fly   218 PSLPDNFFAVTHARLETLNVSCNK-LSTLPRYEQNNHAALVNLSLAGNHLNDSI-FEPLHNAAKL 280
            ..:|.....:  ::|.:|::|.|| |::|| ...:...:|..|.|:|..:.:|. .|.....:.|
plant   822 EEIPARICNL--SQLRSLDISENKRLASLP-VSISELRSLEKLKLSGCSVLESFPLEICQTMSCL 883

  Fly   281 RVLHLAYNRIGVLPAACVRNWPELEILVLSGNMLQQLPEEVATLGQLRVLRCCNNLL-------- 337
            |...|....|..||.. :.|...||:|..|..::::.|..:|.|.:|:||...|:..
plant   884 RWFDLDRTSIKELPEN-IGNLVALEVLQASRTVIRRAPWSIARLTRLQVLAIGNSFFTPEGLLHS 947

  Fly   338 LCTPQLAKLAMLKVLDLSHNHLDRV-----NLLALVPSRNLKYLDLSGN 381
            || |.|::...|:.|.||:.::..:     ||.      ||..||||||
plant   948 LC-PPLSRFDDLRALSLSNMNMTEIPNSIGNLW------NLLELDLSGN 989

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Phlpp	NP_001260558.1	leucine-rich repeat	91..110	CDD:275380	6/19 (32%)
		LRR_8	109..169	CDD:290566	18/108 (17%)
		leucine-rich repeat	111..135	CDD:275380	8/64 (13%)
		leucine-rich repeat	136..158	CDD:275380	6/28 (21%)
		leucine-rich repeat	159..183	CDD:275380	7/24 (29%)
		leucine-rich repeat	184..209	CDD:275380	6/24 (25%)
		LRR_8	205..266	CDD:290566	16/61 (26%)
		leucine-rich repeat	210..230	CDD:275380	2/19 (11%)
		leucine-rich repeat	232..255	CDD:275380	8/23 (35%)
		LRR_RI	<256..410	CDD:238064	42/140 (30%)
		leucine-rich repeat	256..276	CDD:275380	6/20 (30%)
		LRR_8	279..359	CDD:290566	26/87 (30%)
		leucine-rich repeat	280..303	CDD:275380	7/22 (32%)
		leucine-rich repeat	304..348	CDD:275380	15/51 (29%)
		leucine-rich repeat	349..372	CDD:275380	6/27 (22%)
		PP2Cc	461..655	CDD:294085
AT5G17680	NP_001331467.1	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X32
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000