DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Phlpp and AT5G11250

DIOPT Version :9

Sequence 1:	NP_001260558.1	Gene:	Phlpp / 35178	FlyBaseID:	FBgn0032749	Length:	954	Species:	Drosophila melanogaster
Sequence 2:	NP_196686.1	Gene:	AT5G11250 / 830995	AraportID:	AT5G11250	Length:	1189	Species:	Arabidopsis thaliana

Alignment Length:	454	Identity:	93/454 - (20%)
Similarity:	159/454 - (35%)	Gaps:	160/454 - (35%)

- Green bases have known domain annotations that are detailed below.

  Fly    56 SQLGGSILIGNYNYLTQLEVCENEME----VLDLSSLAQLETLKCSRNKLMEL---IINGTNLQT 113
            |.:|.:|.:    .:..|..|.|.:|    :.:..:|.:|:..:|:  ||:||   |.|..|||.
plant   788 SSIGNAINL----LILDLNGCSNLLELPSSIGNAINLQKLDLRRCA--KLLELPSSIGNAINLQN 846

  Fly   114 LVADHNYLHNISTTNTHPVPLKLQRIDISHNNFSELPNWVGACASLTAINASHNRLNNVAVLLRN 178
            |:.|                      |.|  :..|||:.:|...:|..:|.|:
plant   847 LLLD----------------------DCS--SLLELPSSIGNATNLVYMNLSN------------ 875

  Fly   179 YRITELVSLDLAYNDLKQLDQ-FPEGFSSIRSLQLQSNELPSLPDNFFAVTHARLETLNV----S 238
              .:.||.|.|:..:|::|.: ..:|.|.:..|.:..|                ||:|::    .
plant   876 --CSNLVELPLSIGNLQKLQELILKGCSKLEDLPININ----------------LESLDILVLND 922

  Fly   239 CNKLSTLPRYEQNNHAALVNLSLAGNHLNDSIFEPLHNAAKLRVLHLAYNRIGVLPAACVRNWPE 303
            |:.|...|....|                            :|.|:|....|..:|.: :|:||.
plant   923 CSMLKRFPEISTN----------------------------VRALYLCGTAIEEVPLS-IRSWPR 958

  Fly   304 LEILV---------------------LSGNMLQQLPEEVATLGQLRVLRCCNNLLLCTPQLAKLA 347
            |:.|:                     |||..:|::|                      |.:.:::
plant   959 LDELLMSYFDNLVEFPHVLDIITNLDLSGKEIQEVP----------------------PLIKRIS 1001

  Fly   348 MLKVLDLSHNHLDRVNLLALVPSRNLKYLDLSGNLQLQVDEQQFK---------VCQSQSQRHWS 403
            .|:.|.|....  :|..|..:|. :||::|......|:..:..|.         .|...:|....
plant  1002 RLQTLILKGYR--KVVSLPQIPD-SLKWIDAEDCESLERLDCSFHNPEITLFFGKCFKLNQEARD 1063

  Fly   404 LVDVSGNNRAALPTTKIRQVSAQRNQNKTSGPWTMGFAETPGSGDCR-KLSVYQLRAANYGGSD 466
            |:..:...:|.||.   |:|.|......:.|..|:...|.|.....| |..:..:|..:||..|
plant  1064 LIIQTPTKQAVLPG---REVPAYFTHRASGGSLTIKLNERPLPTSMRYKACILLVRIGDYGAHD 1124

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Phlpp	NP_001260558.1	leucine-rich repeat	91..110	CDD:275380	8/21 (38%)
		LRR_8	109..169	CDD:290566	14/59 (24%)
		leucine-rich repeat	111..135	CDD:275380	4/23 (17%)
		leucine-rich repeat	136..158	CDD:275380	6/21 (29%)
		leucine-rich repeat	159..183	CDD:275380	3/23 (13%)
		leucine-rich repeat	184..209	CDD:275380	8/25 (32%)
		LRR_8	205..266	CDD:290566	10/64 (16%)
		leucine-rich repeat	210..230	CDD:275380	2/19 (11%)
		leucine-rich repeat	232..255	CDD:275380	7/26 (27%)
		LRR_RI	<256..410	CDD:238064	30/183 (16%)
		leucine-rich repeat	256..276	CDD:275380	0/19 (0%)
		LRR_8	279..359	CDD:290566	19/100 (19%)
		leucine-rich repeat	280..303	CDD:275380	7/22 (32%)
		leucine-rich repeat	304..348	CDD:275380	8/64 (13%)
		leucine-rich repeat	349..372	CDD:275380	6/22 (27%)
		PP2Cc	461..655	CDD:294085	3/6 (50%)
AT5G11250	NP_196686.1	PLN03210	58..1186	CDD:215633	93/454 (20%)
		leucine-rich repeat	655..677	CDD:275380
		leucine-rich repeat	678..700	CDD:275380
		leucine-rich repeat	701..724	CDD:275380
		leucine-rich repeat	725..747	CDD:275380
		leucine-rich repeat	748..771	CDD:275380
		leucine-rich repeat	772..795	CDD:275380	2/6 (33%)
		leucine-rich repeat	796..819	CDD:275380	4/26 (15%)
		leucine-rich repeat	820..867	CDD:275380	20/72 (28%)
		leucine-rich repeat	868..891	CDD:275380	8/36 (22%)
		leucine-rich repeat	936..958	CDD:275380	7/22 (32%)
		leucine-rich repeat	980..1002	CDD:275380	6/43 (14%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X32
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000